For chemists and R&D scientists immersed in the synthesis of complex organic molecules, a thorough understanding of the chemical profile of intermediates is paramount. Isotridecyl Thioglycolate, identified by its CAS number 137754-72-4, is a compound that warrants close examination for its structural features and potential applications. This article aims to break down the key chemical aspects of this important pharmaceutical intermediate.

At its core, Isotridecyl Thioglycolate is an ester formed from the reaction of thioglycolic acid (also known as mercaptoacetic acid) and isotridecyl alcohol. The molecular formula for this compound is C15H30O2S, which immediately tells us it is a moderately sized organic molecule containing carbon, hydrogen, oxygen, and sulfur. Its molecular weight is approximately 274.4625 g/mol. This molecular weight is significant as it influences properties like volatility, solubility, and reactivity in various chemical processes.

The structure features an isotridecyl group, which is a branched alkyl chain containing thirteen carbon atoms. This lipophilic tail can influence the solubility of the molecule in organic solvents and potentially impact its interaction with biological systems or its behavior in certain formulation types. Attached to this is the thioglycolate ester moiety. The presence of the sulfur atom in the thiol (-SH) group (which is esterified in this case) is particularly noteworthy. Sulfur-containing compounds often exhibit unique chemical reactivities and are integral to many biologically active molecules.

While the specific physical appearance is not detailed in the initial brief, typical esters of this size and type can range from colorless to pale yellow liquids or low-melting point solids at room temperature. Further details regarding melting point, boiling point, and density would be essential for formulators and process chemists to optimize handling and reaction conditions. Accessing a Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) from a reputable supplier is crucial for understanding these physical properties and safety precautions.

In terms of chemical reactivity, the ester linkage is susceptible to hydrolysis, particularly under acidic or basic conditions, yielding thioglycolic acid and isotridecyl alcohol. The ester group can also undergo transesterification reactions. The presence of the sulfur atom, even in an esterified form, can still participate in reactions characteristic of sulfur compounds, such as oxidation or, if the ester is cleaved, participation of the thiol group in nucleophilic reactions or disulfide bond formation.

For scientists looking to buy Isotridecyl Thioglycolate, understanding these chemical properties helps in designing appropriate synthesis strategies. Whether it's being used as a direct building block in API synthesis or as a reagent for introducing specific functional groups, knowing its chemical behavior is key. Sourcing from reliable manufacturers ensures that the compound delivered matches these expected chemical profiles, which is fundamental for reproducible research and development, as well as for industrial-scale production.