In the vast landscape of organic chemistry, certain molecules stand out due to their specific utility and the precise requirements for their production and application. p-(phenylthio)benzyl alcohol, cataloged under CAS number 6317-56-2, is one such compound. It serves as a critical intermediate, particularly noted for its role in pharmaceutical synthesis and its unique chemical characteristics. This article aims to provide a comprehensive overview of its chemical profile, synthesis, and market aspects, guiding potential buyers towards reliable sourcing options.

Chemical Profile and Properties

p-(phenylthio)benzyl alcohol possesses a distinct chemical structure that dictates its reactivity and applications. Its molecular formula is C13H12OS, with a molecular weight of 216.30. Physically, it presents as a pale beige to light beige solid. Key physical properties include:

  • Melting Point: Typically ranging from 46-48°C, indicating its solid state at ambient temperatures.
  • Boiling Point: Approximately 390.2 ± 25.0 °C, signifying its relatively low volatility.
  • Density: Around 1.21 ± 0.1 g/cm³.
  • Purity: Commonly available at purities of 97% or higher, which is critical for its intended uses.

The compound's structure features a benzyl alcohol functional group and a phenylthioether linkage, which are key to its role as a synthetic intermediate. Its EINECS number is 228-658-6.

Synthesis and Manufacturing Insights

The synthesis of p-(phenylthio)benzyl alcohol typically involves the reduction of the corresponding aldehyde, 4-phenylthiobenzaldehyde. Common reducing agents like sodium borohydride are employed, often in alcoholic solvents such as methanol. The reaction is usually carried out under controlled temperatures, followed by standard work-up procedures including neutralization and solvent evaporation. Purification steps are essential to achieve the high purity required by the market. Manufacturers in China are often adept at optimizing these synthesis routes for efficient and cost-effective production, making them key suppliers for this chemical.

Market Dynamics and Applications

The market for p-(phenylthio)benzyl alcohol is primarily driven by its applications:

  • Pharmaceutical Impurity: It is recognized as an impurity in the synthesis of Fenticonazole nitrate, a potent antifungal agent. Therefore, it is in demand as a reference standard for quality control in the pharmaceutical industry.
  • Organic Synthesis Intermediate: Its bifunctional nature makes it a useful building block for creating more complex organic molecules. This includes applications in medicinal chemistry for drug discovery and in the development of specialty materials.

The demand from these sectors ensures a steady market for manufacturers who can consistently produce this compound. When looking to buy, price competitiveness and assured quality are the primary considerations.

Sourcing p-(phenylthio)benzyl Alcohol

For businesses seeking to procure p-(phenylthio)benzyl alcohol, identifying reliable suppliers is key. Manufacturers in China are prominent players in the global market, offering competitive pricing due to efficient production processes and economies of scale. When evaluating suppliers, consider factors such as:

  • Product Specifications: Ensure the purity and physical properties meet your requirements.
  • Pricing: Obtain quotes from multiple suppliers to compare market rates, especially for bulk purchases.
  • Supplier Reliability: Look for suppliers with established track records and good customer feedback.

As a dedicated manufacturer and supplier, we are committed to providing high-quality p-(phenylthio)benzyl alcohol to meet the diverse needs of researchers and industries worldwide. We encourage you to contact us for inquiries about purchasing this valuable chemical intermediate.

Conclusion

p-(phenylthio)benzyl alcohol (CAS 6317-56-2) is a compound with a specific yet critical role in chemical synthesis and pharmaceutical quality control. Its chemical profile, synthesis, and market availability are well-defined, with a strong global supply network. For anyone looking to buy this intermediate, focusing on quality and reliability from established manufacturers is the most strategic approach.