The Chemical Profile of Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate: Properties and Applications
Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate, a chemical compound identified by its CAS number 769195-26-8, is a subject of significant interest within the pharmaceutical intermediate sector. Its molecular formula, C11H9F3O3, and molecular weight of approximately 246.18 highlight its specific chemical composition. As a pale yellow to light yellow solid, its physical characteristics are well-defined, making it recognizable and manageable in laboratory and industrial settings. The compound’s melting point, typically in the range of 40-43°C, and its solubility in solvents like DMSO and methanol, are important parameters for handling and processing.
The primary application driving the demand for this trifluorophenyl intermediate is its indispensable role in the synthesis of Sitagliptin. Sitagliptin, a vital drug for managing type 2 diabetes, requires specific precursors like Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate to achieve its therapeutic effect. The presence of the 2,4,5-trifluorophenyl moiety is crucial for the drug's interaction with its biological target, dipeptidyl peptidase-4 (DPP-4).
NINGBO INNO PHARMCHEM CO.,LTD., as a specialized Sitagliptin intermediate manufacturer in China, ensures that the Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate supplied adheres to high purity standards, often exceeding 98.0% via HPLC. This commitment to quality is vital, as even minor deviations in intermediate purity can impact the efficiency and outcome of complex pharmaceutical syntheses. Understanding the various synonyms, such as 2,4,5-Trifluoro-β-oxo-benzenebutanoic Acid Methyl Ester, further clarifies its identity in chemical literature and supplier catalogs.
For researchers and manufacturers, grasping the complete chemical profile of Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate is key to successful integration into their production workflows. Choosing a reliable pharmaceutical intermediate supplier in China, like NINGBO INNO PHARMCHEM CO.,LTD., ensures you receive a product that meets stringent specifications for your Sitagliptin production needs, contributing to the development of effective diabetes treatments.
The primary application driving the demand for this trifluorophenyl intermediate is its indispensable role in the synthesis of Sitagliptin. Sitagliptin, a vital drug for managing type 2 diabetes, requires specific precursors like Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate to achieve its therapeutic effect. The presence of the 2,4,5-trifluorophenyl moiety is crucial for the drug's interaction with its biological target, dipeptidyl peptidase-4 (DPP-4).
NINGBO INNO PHARMCHEM CO.,LTD., as a specialized Sitagliptin intermediate manufacturer in China, ensures that the Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate supplied adheres to high purity standards, often exceeding 98.0% via HPLC. This commitment to quality is vital, as even minor deviations in intermediate purity can impact the efficiency and outcome of complex pharmaceutical syntheses. Understanding the various synonyms, such as 2,4,5-Trifluoro-β-oxo-benzenebutanoic Acid Methyl Ester, further clarifies its identity in chemical literature and supplier catalogs.
For researchers and manufacturers, grasping the complete chemical profile of Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate is key to successful integration into their production workflows. Choosing a reliable pharmaceutical intermediate supplier in China, like NINGBO INNO PHARMCHEM CO.,LTD., ensures you receive a product that meets stringent specifications for your Sitagliptin production needs, contributing to the development of effective diabetes treatments.
Perspectives & Insights
Nano Explorer 01
“The compound’s melting point, typically in the range of 40-43°C, and its solubility in solvents like DMSO and methanol, are important parameters for handling and processing.”
Data Catalyst One
“The primary application driving the demand for this trifluorophenyl intermediate is its indispensable role in the synthesis of Sitagliptin.”
Chem Thinker Labs
“Sitagliptin, a vital drug for managing type 2 diabetes, requires specific precursors like Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate to achieve its therapeutic effect.”