For professionals in the pharmaceutical and chemical industries, a thorough understanding of a compound's properties is fundamental to its effective use. N-Methylnorbuprenorphine 3-Methyl Ether, identified by its CAS number 16196-70-6, is a compound of significant interest as a pharmaceutical intermediate and a component in diagnostic reagents. Examining its chemical and physical profile provides insight into its handling, application, and quality requirements.

Chemical Identity and Structure

N-Methylnorbuprenorphine 3-Methyl Ether is a derivative of Buprenorphine, a molecule known for its complex pharmacological activity. Its precise chemical identification is crucial for research and regulatory purposes.

  • Chemical Name: N-Methylnorbuprenorphine 3-Methyl Ether
  • CAS Number: 16196-70-6
  • Molecular Formula: C27H39NO4
  • Molecular Weight: 441.60286

The molecular structure is intricate, indicating specific stereochemistry that is vital for its biological activity and use in synthesis. This complexity underscores the importance of sourcing from manufacturers capable of precise chemical synthesis.

Physical Properties and Characteristics

Understanding the physical state and appearance of a chemical intermediate is essential for proper identification, storage, and initial quality assessment.

  • Appearance: Typically described as a creamish white to off-white powder. This visual characteristic is a primary indicator of the compound's state and can be a first-pass check for potential contamination or degradation.
  • Solubility and Stability: While specific solubility data for N-Methylnorbuprenorphine 3-Methyl Ether may vary based on the solvent, its nature as an organic molecule suggests solubility in various organic solvents. Stability is usually maintained under recommended storage conditions, often involving room temperature and protection from light.

Applications and Significance

The value of N-Methylnorbuprenorphine 3-Methyl Ether lies primarily in its application as:

  • A Pharmaceutical Intermediate: It serves as a building block or precursor in the synthesis of various pharmaceutical compounds.
  • A Diagnostic Reagent Component: Its specific properties make it useful in the development of analytical tools and reagents for quality control and research in the pharmaceutical sector.

Sourcing Considerations

When procuring N-Methylnorbuprenorphine 3-Methyl Ether, it is crucial to partner with suppliers who can guarantee the specified purity and consistent physical properties. Manufacturers specializing in pharmaceutical intermediates, often found in China, provide detailed technical data, including CoAs that confirm the molecular weight and purity, ensuring that researchers and developers receive reliable materials for their critical applications. Ensuring proper handling and storage according to supplier recommendations is also key to maintaining the compound's integrity.

In essence, the chemical and physical profile of N-Methylnorbuprenorphine 3-Methyl Ether highlights its specialized nature and the need for precise manufacturing and rigorous quality control from its suppliers.