The Chemical Profile of 2-Piperidone: Properties and Handling Guide
For professionals in the chemical and pharmaceutical industries, a thorough understanding of a compound's properties and safe handling practices is fundamental. 2-Piperidone, or hexahydro-2-pyridinone (CAS 675-20-7), is a valuable organic intermediate known for its diverse applications. This guide provides essential details on its chemical profile, enabling informed procurement and usage decisions.
Physical and Chemical Properties: 2-Piperidone typically presents as a colorless to light yellow liquid or crystalline solid at room temperature, with a melting point around 26-28 °C. It exhibits a high boiling point of approximately 218-220 °C at atmospheric pressure. Its solubility profile is notable: it is highly soluble in polar solvents such as water, ethanol, and acetone, and sparingly soluble in nonpolar solvents like benzene. This solubility makes it an excellent organic synthesis solvent and facilitates its use in aqueous reaction systems.
Stability and Reactivity: The compound is considered stable under recommended storage conditions, which include keeping it in a sealed container in a cool, dry place, away from oxidizers and strong acids, and protected from moisture due to its hygroscopic nature. Understanding its stability is crucial for users looking to buy 2-piperidone for long-term applications.
Safety and Handling: While classified as having low toxicity (LD50 rat, oral ~2000 mg/kg), 2-Piperidone is an irritant to skin, eyes, and the respiratory tract. Proper safety measures, including wearing gloves and goggles and using it in well-ventilated areas, are essential. In case of skin contact, immediate rinsing with soapy water is recommended. For any industrial-scale operations, it's advisable to consult the full Safety Data Sheet (SDS) provided by the manufacturer or supplier.
When you purchase 2-piperidone, ensuring you have accurate data on its properties and handling is as important as the purity itself. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. are committed to providing this information to support your R&D and production needs. This detailed understanding empowers users to safely and effectively leverage 2-Piperidone in their various chemical synthesis endeavors.
Perspectives & Insights
Alpha Spark Labs
“Its solubility profile is notable: it is highly soluble in polar solvents such as water, ethanol, and acetone, and sparingly soluble in nonpolar solvents like benzene.”
Future Pioneer 88
“This solubility makes it an excellent organic synthesis solvent and facilitates its use in aqueous reaction systems.”
Core Explorer Pro
“Stability and Reactivity: The compound is considered stable under recommended storage conditions, which include keeping it in a sealed container in a cool, dry place, away from oxidizers and strong acids, and protected from moisture due to its hygroscopic nature.”