For researchers and developers in the pharmaceutical industry, a deep understanding of the chemical properties and synthesis of intermediates is paramount. 7-ACT, identified by CAS 131257-07-3, is a crucial intermediate in the production of cephalosporin antibiotics, most notably Ceftriaxone Sodium. Its specific molecular structure, purity, and reactivity are key factors that influence its utility in complex synthetic processes. This article aims to provide a detailed chemical profile of 7-ACT, offering insights relevant to R&D professionals seeking to purchase or work with this compound. As a dedicated supplier of 7-ACT, we focus on delivering products with well-defined chemical characteristics.

7-ACT, chemically known as Sodium (6R,7R)-7-amino-3-(((6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, possesses a molecular formula of C₁₂H₁₃N₅O₅S₂ and a molecular weight of 371.39 g/mol. Its physical appearance as a white to off-white solid, along with a purity typically exceeding 99%, makes it a reliable starting material for pharmaceutical synthesis. The presence of the β-lactam ring fused with a complex triazine moiety is central to its functionality. Researchers often seek this precise structural integrity when they buy 7-ACT for their synthetic endeavors.

The synthesis of 7-ACT itself involves intricate chemical transformations. Historically, methods for deprotecting cephalosporin nuclei often involved harsh conditions that could degrade the sensitive β-lactam ring. Advancements, such as BF₃·CH₃CN-mediated deacylation and the use of ethyl acetate as an extraction solvent, have significantly improved yields and purity, making large-scale production more feasible. Understanding these synthetic pathways can be beneficial for R&D scientists when troubleshooting processes or exploring alternative routes. When engaging with a manufacturer of 7-ACT, inquiring about their synthesis methods and quality control procedures can provide valuable insights into product consistency.

The primary application of 7-ACT is as a key intermediate in the synthesis of Ceftriaxone Sodium, a widely used third-generation cephalosporin antibiotic. The reactivity of the amino group at the C-7 position allows for facile acylation with the specific side chain that imparts broad-spectrum antibacterial activity. This makes 7-ACT an indispensable component for companies manufacturing this important API. For research and development purposes, understanding these reaction mechanisms is crucial for optimizing synthetic yields and developing new cephalosporin derivatives. If you are looking to purchase 7-ACT for R&D, its chemical profile is a significant asset.

Beyond its primary role, 7-ACT can also be studied for its own chemical properties, such as cocrystal formation or polymorphism, which can influence its solubility and bioavailability in derivative drugs. Its well-defined nature also makes it suitable as a reference standard in analytical chemistry for quality assurance in pharmaceutical production. When considering sourcing this intermediate, a commitment to high purity and detailed chemical specifications from your pharmaceutical intermediate supplier is essential for successful research and development outcomes.

In summary, 7-ACT is a chemically sophisticated intermediate with critical applications in the pharmaceutical industry. Its precise structure, high purity, and specific reactivity make it indispensable for the production of vital cephalosporin antibiotics. For R&D professionals, understanding its chemical profile and ensuring a reliable supply from expert manufacturers is key to advancing drug development. We encourage you to contact us for your high-quality 7-ACT needs and to discuss how our product can support your research and manufacturing goals.