For chemists and R&D scientists in the pharmaceutical and fine chemical industries, a deep understanding of the chemical profile of key intermediates is fundamental to successful synthesis. 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, identified by CAS number 93107-30-3, is one such critical compound, recognized for its indispensable role in the development of powerful antibacterial agents. This article outlines its key chemical characteristics and its significance in advanced organic synthesis.

The molecular structure of CAS 93107-30-3 is characterized by a difluorinated quinoline core, functionalized with a cyclopropyl group at the N1 position and a carboxylic acid group at C3. The presence of a keto group at C4 and the dihydro nature of the ring system contribute to its specific reactivity and chemical properties. With a molecular formula of C13H9F2NO3 and a molecular weight of approximately 265.21 g/mol, this compound is a relatively complex organic molecule. Its physical form is typically a solid, often described as an off-white powder or crystals, with a notable melting point of around 289°C (lit.). This high melting point suggests a stable crystalline structure.

The difluoro substitution at the 6 and 7 positions is particularly important. Fluorine atoms are known to significantly influence the lipophilicity, metabolic stability, and binding affinity of pharmaceutical compounds. In the context of fluoroquinolone antibiotics, these fluorine atoms are often crucial for enhancing penetration into bacterial cells and increasing the potency of the drug. The carboxylic acid group provides a site for further chemical modification, such as esterification or amide formation, which are common steps in drug synthesis pathways. The quinolone ring system itself is the pharmacophore that interacts with bacterial enzymes, and the substituents modulate its overall effectiveness and spectrum of activity.

As a well-established intermediate for the synthesis of antibiotics like Moxifloxacin, CAS 93107-30-3 is highly sought after by pharmaceutical manufacturers. Its production requires precise control over reaction conditions and purification processes to ensure the high purity necessary for API synthesis. When you are looking to purchase this intermediate, engaging with suppliers who can reliably deliver material meeting strict specifications is paramount. Manufacturers in China are a significant source for this compound, offering competitive pricing and large-scale production capabilities. Ensuring you buy from a trustworthy manufacturer or supplier means you are investing in the quality and success of your research and development efforts.

In summary, the detailed chemical profile of 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid (CAS 93107-30-3) underscores its critical importance in the pharmaceutical industry. Its unique structure and properties make it an indispensable intermediate for creating advanced antibacterial agents. If you are a researcher or procurement manager seeking to purchase this high-value chemical, consider partnering with experienced manufacturers for a consistent and high-quality supply.