Understanding the chemical profile of key intermediates is essential for their effective application in synthesis. Tetrahydrofuran-2-carboxylic acid (CAS 16874-33-2), a heterocyclic compound, possesses a set of properties that make it highly valuable in the chemical and pharmaceutical industries. NINGBO INNO PHARMCHEM CO.,LTD. provides this compound and supports understanding its characteristics and synthesis.

The basic chemical properties of Tetrahydrofuran-2-carboxylic acid include its molecular formula C5H8O3 and a molecular weight of approximately 116.12 g/mol. It typically appears as a colorless to light yellow liquid. Its melting point is around 21°C, and it has a boiling point of approximately 135°C at 20 mmHg. The density is reported to be around 1.209 g/mL at 25°C. These physical properties are crucial for handling, storage, and process design in industrial settings. NINGBO INNO PHARMCHEM CO.,LTD. ensures that these properties are maintained within specified ranges for its product.

The synthesis of Tetrahydrofuran-2-carboxylic acid often involves the reduction of 2-furoic acid. Various methods have been developed, including selective hydrogenation over bimetallic catalysts. The enantioselective synthesis of chiral forms, such as (R)-2-THFA, can be achieved through processes like enantioselective heterogeneous or homogeneous hydrogenation using chiral catalysts. The availability of these synthesis routes allows for the production of the compound with the required purity and stereochemistry, catering to specific application needs.

For pharmaceutical intermediates, the synthesis pathway and the resulting purity are critical. The use of Tetrahydrofuran-2-carboxylic acid as a precursor in the synthesis of drugs like Terazosin, Alfuzosin, and Faropenem highlights the importance of its availability and quality. The pharmaceutical industry relies on precise synthesis to ensure the efficacy and safety of medications. NINGBO INNO PHARMCHEM CO.,LTD. plays a vital role in this by supplying a well-characterized and high-quality intermediate.

In essence, Tetrahydrofuran-2-carboxylic acid's chemical properties and the sophisticated synthesis methods employed to produce it underscore its importance as a versatile chemical intermediate. NINGBO INNO PHARMCHEM CO.,LTD. continues to be a reliable partner for industries that depend on this compound, facilitating advancements in pharmaceuticals, chemicals, and beyond.