Trans-4-Hydroxycyclohexanecarboxylic Acid (CAS 3685-26-5) is a fascinating organic compound that plays a vital role as an intermediate in numerous chemical synthesis pathways. Understanding its precise chemical profile – from molecular structure to physical properties and synthesis methods – is crucial for R&D scientists and procurement specialists aiming to leverage its potential.

At its core, Trans-4-Hydroxycyclohexanecarboxylic Acid is a derivative of cyclohexane, featuring a hydroxyl (-OH) group and a carboxylic acid (-COOH) group attached to the ring. The 'trans' designation indicates that these two functional groups are positioned on opposite sides of the cyclohexane ring. This specific spatial arrangement, known as stereochemistry, dictates much of its reactivity and its suitability for particular synthetic transformations.

Key chemical and physical properties often cited for this compound include:

  • Molecular Formula: C7H12O3
  • Molecular Weight: 144.17 g/mol
  • Appearance: Typically a white to off-white solid or powder.
  • Purity: High purity grades, often 99% or greater, are commonly available from specialized manufacturers.
  • CAS Number: 3685-26-5

The presence of both a hydroxyl and a carboxylic acid functional group makes Trans-4-Hydroxycyclohexanecarboxylic Acid a bifunctional molecule, capable of undergoing a wide range of reactions. The hydroxyl group can participate in esterification, etherification, and oxidation, while the carboxylic acid group can form salts, esters, amides, and acyl halides. This dual reactivity makes it an invaluable building block in organic synthesis.

From a synthesis perspective, Trans-4-Hydroxycyclohexanecarboxylic Acid can be produced through various routes. One common method involves the catalytic hydrogenation of p-hydroxybenzoic acid, followed by isomerization to favor the trans isomer. Manufacturers may also employ specific microbial synthesis or enzymatic approaches to achieve high stereoselectivity and purity. When you buy this compound, understanding its synthesis route can provide insights into its potential impurity profile.

Its primary application lies as an intermediate in the synthesis of pharmaceuticals and agrochemicals. For example, it can be used in the preparation of certain drug scaffolds or as a precursor for more complex organic molecules. Researchers looking to purchase this compound for R&D purposes benefit from its well-defined structure and predictable reactivity.

For businesses requiring a reliable supply of Trans-4-Hydroxycyclohexanecarboxylic Acid, partnering with an experienced chemical manufacturer is essential. Companies in China, for instance, are significant players in the global supply of such fine chemicals, often providing competitive price options for bulk quantities. When you inquire about price or availability, it is beneficial to ask about the detailed analytical data supporting the purity claims.

In summary, the chemical profile of Trans-4-Hydroxycyclohexanecarboxylic Acid is characterized by its precise trans stereochemistry and versatile bifunctionality. As a high-purity intermediate, it is indispensable for advanced organic synthesis. If your work requires this compound, exploring options from reputable suppliers and manufacturers is the first step to successful project outcomes.