trans-4-Methylcyclohexylamine hydrochloride, identified by its CAS number 33483-65-7, is a chemical compound that holds significant value in various industrial applications. Understanding its chemical profile, including its physical and chemical properties, as well as safety and handling guidelines, is crucial for its effective and safe utilization in research and manufacturing. This article provides an overview of these key aspects, essential for procurement managers, R&D scientists, and formulation chemists.

The compound's molecular formula is C7H16ClN, with a molecular weight of approximately 149.66 g/mol. It typically appears as a white to off-white solid, indicative of its purity. A notable physical property is its high melting point, around 260°C, which suggests considerable thermal stability. As a hydrochloride salt of an amine, it exhibits increased solubility in polar solvents, including water, which is advantageous for many chemical reactions and formulations. Its structure features a cyclohexane ring with a methyl group in the trans position and an amine functional group, which is the basis of its reactivity.

Chemically, the amine group in trans-4-Methylcyclohexylamine hydrochloride can participate in a variety of reactions. It can act as a nucleophile, forming amide bonds, or react with electrophiles. This versatility makes it a valuable intermediate for synthesizing more complex organic molecules. The presence of the hydrochloride counter-ion influences its solubility and basicity. Information regarding its logP value, hydrogen bond donors and acceptors, and rotatable bonds provides further insights into its behavior in chemical systems, aiding in formulation and process design.

Safety considerations are paramount when handling this chemical. According to GHS classifications, trans-4-Methylcyclohexylamine hydrochloride is associated with hazard statements such as H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Therefore, appropriate personal protective equipment (PPE) is essential. This includes chemical-resistant gloves, eye protection (safety goggles or face shield), and protective clothing. Work should be conducted in a well-ventilated area or under a fume hood to minimize inhalation exposure. Always refer to the Safety Data Sheet (SDS) provided by the supplier for comprehensive safety information and emergency procedures.

Storage recommendations typically include keeping the compound in a tightly sealed container in a dry, cool, and well-ventilated place, away from incompatible materials. Proper storage ensures the integrity and longevity of the chemical. For companies looking to buy this compound, understanding these chemical and safety properties empowers them to make informed decisions regarding its application, handling, and sourcing from reliable manufacturers that provide detailed technical and safety documentation.