For R&D scientists and product formulators, a deep understanding of chemical properties is fundamental when selecting intermediates for pharmaceutical synthesis. 1H-Pyrrolo[2,3-b]pyridin-5-ol, also known as 5-Hydroxy-7-azaindole (CAS 98549-88-3), is a prime example of a compound where precise chemical characteristics dictate its suitability and performance. As a key intermediate, particularly for compounds like ABT-199, its physical and chemical properties are meticulously controlled by reputable manufacturers.

The molecular formula C7H6N2O and a molecular weight of approximately 134.13 are just the starting point. When you plan to buy this material, you should look for detailed specifications that go beyond basic identifiers. For instance, its melting point, typically between 219-220°C, is a critical indicator of purity. Its appearance as a white to off-white powder is also a standard characteristic. For procurement managers, understanding parameters like density (around 1.4 g/cm³) and flash point (around 177°C) is important for handling, storage, and safety protocols.

The purity of 5-Hydroxy-7-azaindole is paramount for its application as a pharmaceutical intermediate. A high purity of ≥98.0%, coupled with strict controls on single impurities (≤0.15%) and other impurities (≤0.1%), is essential. This ensures that the synthesis process remains clean and that the final API, such as ABT-199, meets regulatory requirements without unforeseen side reactions or contaminants. When sourcing from a supplier in China, verifying these specifications against your project’s needs is key. Obtaining a detailed certificate of analysis (CoA) from the manufacturer is a standard practice for quality assurance.

Choosing the right chemical supplier involves evaluating not just the price, but also the consistency and reliability of the product. For R&D scientists, the ability to reliably purchase high-quality intermediates enables smoother experimental progression and faster development cycles. As a dedicated manufacturer, we ensure that each batch of 1H-Pyrrolo[2,3-b]pyridin-5-ol upholds these critical properties, supporting your research and production goals.