For chemists and product formulators, a deep understanding of a chemical compound's properties is fundamental to its successful application. 2-(4-Bromothiophen-2-yl)acetic Acid (CAS: 161942-89-8) is a prime example of a versatile intermediate whose utility is defined by its unique chemical characteristics. Whether you are looking to buy 2-(4-bromothiophen-2-yl)acetic acid for synthesis or research, knowing these properties is essential.

Molecular Structure and Identity

The chemical identity of 2-(4-Bromothiophen-2-yl)acetic Acid is encapsulated by its molecular formula, C6H5BrO2S, and its specific CAS Registry Number, 161942-89-8. Structurally, it features a thiophene ring, a five-membered heterocyclic aromatic ring containing sulfur. This ring is substituted at the 4-position with a bromine atom and at the 2-position with an acetic acid group (-CH2COOH). This arrangement provides distinct reactive sites: the bromine atom is amenable to various coupling reactions (like palladium-catalyzed cross-couplings), while the carboxylic acid group can undergo esterification, amidation, or salt formation.

Key Physical and Chemical Properties

Understanding the physical properties of 2-(4-Bromothiophen-2-yl)acetic Acid is vital for handling and processing:

  • Appearance: It is typically described as a white solid, making it convenient for weighing and manipulation in laboratory settings.
  • Melting Point: A critical indicator of purity, its melting point is reported in the range of 87-92°C. Variations outside this range might suggest the presence of impurities.
  • Solubility: While specific solubility data may vary, such organic acids are generally soluble in common organic solvents like ethanol, methanol, and DMSO, and may have limited solubility in water.
  • Reactivity: The presence of the bromine atom makes it an excellent substrate for electrophilic aromatic substitution and transition metal-catalyzed cross-coupling reactions. The acidic proton of the carboxylic acid group can be readily removed by bases.

Sourcing High-Quality Intermediates

For researchers and manufacturers, sourcing this compound requires attention to detail. A reliable 2-(4-bromothiophen-2-yl)acetic acid supplier China-based, such as NINGBO INNO PHARMCHEM CO.,LTD., is crucial. They can provide detailed specifications, ensuring the chemical meets the required purity and characteristics. Enquiring about CAS 161942-89-8 prices and requesting a Certificate of Analysis (CoA) are standard practices when evaluating a 2-(4-bromothiophen-2-yl)acetic acid manufacturer.

In summary, the chemical properties of 2-(4-Bromothiophen-2-yl)acetic Acid, including its molecular structure, functional groups, and physical attributes, dictate its broad utility in synthesis. By partnering with knowledgeable suppliers, chemists can ensure they acquire high-quality intermediates for their critical research and development projects.