For professionals in the chemical and pharmaceutical industries, a deep understanding of the properties of key intermediates is fundamental to successful synthesis and product development. 3-(2-Bromo-1-oxopropyl)-spiro[2H-1,3-benzoxazine-2,1'-cyclohexan]-4(3H)-one, identified by CAS number 158299-05-9, is one such compound, serving as a crucial intermediate in the synthesis of important pharmaceuticals like Meropenem.

This article focuses on the chemical characteristics of CAS 158299-05-9. From a structural perspective, it features a spirocyclic system that incorporates a benzoxazine ring fused to a cyclohexane ring, with a bromo-substituted propionyl group attached to the nitrogen atom of the benzoxazine. Its molecular formula is C16H18BrNO3, and it has a molecular weight of 352.21 g/mol. The appearance of this compound is typically a white powder, indicating a high degree of purity essential for pharmaceutical applications. The provided purity level is usually around 98%.

The presence of the bromine atom in the propionyl chain makes this molecule highly reactive, serving as an excellent electrophilic site for nucleophilic substitution reactions. This reactivity is key to its utility as a pharmaceutical intermediate, allowing for its incorporation into more complex molecular structures through various synthetic pathways. Its role as a Meropenem intermediate is well-established, where it contributes a critical part of the carbapenem structure.

When considering the purchase of such a specialized chemical, buyers often seek information on its physical and chemical properties, storage conditions, and handling precautions. Reliable suppliers will offer comprehensive documentation to support safe and effective use. For those looking to buy this compound, understanding these properties ensures that it can be integrated seamlessly into their research or manufacturing processes. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier committed to providing chemicals with detailed specifications and consistent quality. If you are interested in learning more or purchasing 3-(2-Bromo-1-oxopropyl)-spiro[2H-1,3-benzoxazine-2,1'-cyclohexan]-4(3H)-one, we encourage you to reach out to us for detailed product information and a competitive quote.