For chemists and material scientists, a deep understanding of a compound's chemical properties is fundamental to its successful application. 5-Aminoisophthalic Acid (CAS 99-31-0) is a fascinating molecule whose versatile reactivity and physical characteristics make it invaluable in various fields, from organic synthesis to materials science. As a leading supplier, NINGBO INNO PHARMCHEM CO.,LTD. provides high-purity 5-Aminoisophthalic Acid and aims to equip our clients with the knowledge to effectively utilize it.

Molecular Structure and Key Functional Groups

The chemical identity of 5-Aminoisophthalic Acid (5-AIPA) is defined by its molecular formula, C8H7NO4, and a molecular weight of 181.15 g/mol. Its structure features a benzene ring with two carboxylic acid (-COOH) groups at the 1 and 3 positions, and an amino (-NH2) group at the 5 position. This arrangement imparts several key characteristics:

  • Acidity: The two carboxylic acid groups contribute acidic properties, allowing it to participate in esterification, salt formation, and coordination with metal ions.
  • Basicity: The amino group provides basic properties and can act as a nucleophile or be involved in reactions like acylation and diazotization.
  • Aromaticity: The benzene ring offers stability and is susceptible to electrophilic aromatic substitution under specific conditions.

This trifunctional nature makes 5-Aminoisophthalic Acid an excellent building block for creating complex organic molecules and polymers.

Physical Properties: Appearance, Solubility, and Stability

Typically, 5-Aminoisophthalic Acid presents as an Off-white crystalline powder. Its physical form is important for handling and processing. Key physical properties include:

  • Melting Point: It has a very high melting point, often reported as >300°C (lit.), indicating excellent thermal stability. This robustness is crucial for applications that involve high-temperature processing.
  • Solubility: 5-Aminoisophthalic Acid is generally described as insoluble in water. However, it shows some solubility in polar organic solvents such as DMSO and limited solubility in alcohols. This differential solubility can be exploited in synthesis and purification processes.
  • Density: Its density is estimated to be around 1.4283 to 1.551 g/cm³.

Regarding storage, it is recommended to keep the compound in a cool, dry place, in tightly closed containers, away from incompatible substances, to maintain its stability over time. This is a critical aspect for any buy 5-aminoisophthalic acid order.

Spectroscopic Characteristics

Spectroscopic techniques are vital for confirming the identity and purity of 5-Aminoisophthalic Acid. Standard characterization methods include:

  • FT-IR Spectroscopy: Reveals characteristic absorption bands for N-H stretches (amine), C=O stretches (carboxylic acid dimer), and C-N stretches, confirming the presence of these functional groups.
  • NMR Spectroscopy (¹H and ¹³C): Provides detailed structural information, allowing for unambiguous identification and purity assessment. The proton NMR, for example, will show distinct signals for the aromatic protons and the amine protons.
  • UV-Vis Spectroscopy: The conjugated aromatic system exhibits characteristic UV absorption, which can be used for quantitative analysis.

These spectroscopic fingerprints are essential quality control parameters provided by reputable 5-aminoisophthalic acid manufacturer china like NINGBO INNO PHARMCHEM CO.,LTD.

Reactivity and Applications

The dual nature of the carboxylic acid groups and the presence of the amino group endow 5-Aminoisophthalic Acid with diverse reactivity. It is extensively used as a ligand in the synthesis of Metal-Organic Frameworks (MOFs), where its coordination capabilities form the backbone of these porous materials. Furthermore, it serves as a crucial intermediate in the synthesis of pharmaceuticals, dyes, and other fine chemicals. Its ability to undergo esterification, amidation, and participate in polymerization reactions makes it a flexible component in advanced organic synthesis.

For researchers and procurement specialists seeking reliable sources of high purity 5-aminoisophthalic acid for sale, understanding these chemical properties is key to ensuring successful outcomes. Partnering with a knowledgeable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures you receive a product that is not only chemically sound but also backed by technical expertise.