For chemists and chemical engineers, understanding the detailed properties of chemical compounds is fundamental to their successful application. 6-Chloro-2-hexanone, identified by CAS number 10226-30-9, is a compound of significant interest due to its bifunctional nature and its role as a versatile intermediate. This article delves into the key chemical and physical properties of 6-Chloro-2-hexanone, offering insights relevant to R&D scientists and procurement managers.

Physical Characteristics of 6-Chloro-2-hexanone

Typically, 6-Chloro-2-hexanone is described as a clear liquid, ranging in color from yellow to brown. This physical appearance is common for many organic compounds and can sometimes indicate slight impurities or degradation over time, underscoring the importance of proper storage and handling. The compound's density is approximately 1.02 g/mL at 25°C, and its refractive index (n20/D) is noted as 1.4435, providing key parameters for quality control and identification.

With a boiling point of approximately 85.5-86.5 °C at 16 mmHg, it is a moderately volatile compound. Its flash point is around 91°C, classifying it as a combustible liquid that requires appropriate safety precautions during handling and storage. Notably, 6-Chloro-2-hexanone is insoluble in water but exhibits good solubility in common organic solvents such as chloroform, n-heptane, and ethanol, which is advantageous for its use in various reaction media.

Chemical Reactivity and Applications

The chemical reactivity of 6-Chloro-2-hexanone is governed by two primary functional groups: the ketone (carbonyl) and the alkyl chloride. The ketone group can participate in nucleophilic addition reactions, condensation reactions, and reductions. The C-Cl bond is susceptible to nucleophilic substitution reactions, allowing for the introduction of various other functional groups or the extension of carbon chains.

This dual reactivity makes it an invaluable organic building block. Its most prominent application is as a key intermediate in the synthesis of Pentoxifylline, an API used for improving blood circulation. By reacting with specific reagents, the molecule undergoes transformations to form the desired pharmaceutical product. For anyone looking to buy 6-Chloro-2-hexanone for such applications, ensuring high purity (u226599%) is crucial for successful synthesis.

Sourcing High-Quality 6-Chloro-2-hexanone

NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-purity 6-Chloro-2-hexanone. As a leading manufacturer and supplier in China, we ensure our product meets the stringent requirements of the pharmaceutical and fine chemical industries. Our commitment to quality means you can confidently purchase 6-Chloro-2-hexanone for your critical synthesis needs. We provide comprehensive product information, including COAs and MSDS, to support your R&D and procurement processes.

Engage with us to secure a reliable supply of this important intermediate. Contact NINGBO INNO PHARMCHEM CO.,LTD. today for inquiries on CAS 10226-30-9 and to learn more about our product offerings.