Understanding the chemical intricacies of key synthesis reagents is fundamental for any scientist or chemist. Boc-Cys(Acm)-OH, scientifically known as N-Boc-S-acetamidomethyl-L-cysteine with CAS number 19746-37-3, is a prime example of such a critical building block. As a specialized chemical supplier, we are dedicated to providing insights into the properties and diverse applications of this valuable amino acid derivative, crucial for advanced organic synthesis and biochemical research.

The molecular structure of Boc-Cys(Acm)-OH combines several key features that make it exceptionally useful. The N-terminal Boc protection is standard in solid-phase peptide synthesis (SPPS), offering facile deprotection under acidic conditions without disturbing other sensitive functional groups. The defining characteristic, however, is the S-acetamidomethyl (Acm) group attached to the thiol of cysteine. This specific protection strategy allows for the selective formation of disulfide bonds. The Acm group is stable under the Boc deprotection conditions and can be cleaved using reagents like iodine (I2), which simultaneously oxidizes the free thiols to form the desired disulfide linkage (-S-S-). This controlled reactivity is essential for synthesizing peptides with specific conformational constraints, such as cyclic peptides used in therapeutics.

Physically, Boc-Cys(Acm)-OH is typically supplied as a white powder, with a melting point often cited in the range of 103-117°C or 111-114°C depending on the source. Its molecular weight is approximately 292.35 g/mol, with the chemical formula C11H20N2O5S. These properties are standard for a high-purity amino acid derivative. When you buy Boc-Cys(Acm)-OH, you are investing in a reagent that facilitates complex molecular architecture.

The applications of Boc-Cys(Acm)-OH are widespread. Its primary use is in the synthesis of peptides requiring disulfide bonds for their biological activity or structural stability. This includes a broad range of therapeutic peptides and protein mimics. Beyond this, it serves as an invaluable tool in protein modification studies, enabling researchers to selectively label cysteine residues for detection, purification, or to study protein-ligand interactions. For scientists seeking to buy CAS 19746-37-3 for these specialized applications, partnering with a reliable manufacturer in China ensures access to a product that meets stringent purity and chemical specifications. We are proud to be that supplier.

In summary, the chemical properties of Boc-Cys(Acm)-OH, particularly its dual protection strategy, make it a cornerstone reagent for modern synthetic chemistry. Its utility in forming disulfide bonds in peptides and its applications in protein modification highlight its importance. As a dedicated manufacturer and supplier, we encourage you to consider our high-purity Boc-Cys(Acm)-OH for your research needs. Contact us for detailed specifications, pricing, and to place an order.