The field of organic chemistry constantly unveils molecules with intricate structures and diverse applications, particularly in the pharmaceutical industry. Among these, (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid stands out as a significant chiral intermediate. This article delves into its key chemical and physical properties, its characteristic appearance, and its primary applications, highlighting its importance in chemical synthesis. NINGBO INNO PHARMCHEM CO.,LTD. is a key player in supplying this essential compound.

Chemically, (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid is characterized by its molecular formula C9H15NO2 and a molecular weight of 169.221 g/mol. Its structure features a saturated indole ring system with a carboxylic acid group attached, conferring specific reactivity and solubility. The compound typically presents as an off-white to light yellow crystalline powder, a visual cue for its purity and form. Its melting point, generally between 252-260°C (with some variations reported depending on the specific analysis, such as decomposition points), indicates its solid-state stability under normal conditions. The optical rotation, a critical parameter for chiral compounds, typically falls within the range of -44.0° to -50.0°, confirming its enantiomeric purity.

The primary application of (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid is as a vital intermediate in the synthesis of Perindopril, a critical medication used to treat hypertension and heart failure. The compound's specific stereochemistry is essential for the biological activity of Perindopril. Beyond this primary use, its structural features make it a valuable building block in other complex organic synthesis endeavors, particularly those requiring chiral resolution or specific ring structures. Sourcing this compound from reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures that manufacturers receive materials that meet stringent quality specifications for assay (≥98.0%), loss on drying (≤0.5%), and residue on ignition (≤0.5%).

The demand for high-purity pharmaceutical intermediates like (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid fuels a specialized segment of the chemical industry. Manufacturers invest heavily in sophisticated synthesis and purification techniques to achieve the required levels of purity and stereochemical integrity. When you purchase (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid, you are engaging with a product that has undergone rigorous quality control. The competitive price point from suppliers like NINGBO INNO PHARMCHEM CO.,LTD. reflects their advanced manufacturing capabilities and efficient supply chain management.

In conclusion, (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid is a testament to the precision required in pharmaceutical chemistry. Its distinct properties, coupled with its indispensable role in the synthesis of Perindopril, make it a cornerstone intermediate. For anyone looking to buy this compound, understanding its chemical profile and the importance of sourcing from trusted manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. is key to successful pharmaceutical development and production.