The Chemical Properties and Synthesis Applications of 4-Chloro-2-butanone
Understanding the fundamental chemical properties of key intermediates is crucial for chemists aiming to develop new compounds and optimize synthesis pathways. 4-Chloro-2-butanone (CAS 6322-49-2), a halogenated ketone, possesses a unique set of characteristics that make it a highly sought-after building block in organic synthesis, particularly for the pharmaceutical and agrochemical industries. Its molecular structure (C4H7ClO) and reactivity profile enable a diverse range of chemical transformations.
The physicochemical properties of 4-Chloro-2-butanone are well-documented, typically including its appearance as a colorless to pale yellow liquid, a boiling point around 145-155°C, and a flash point of approximately 45.5°C. Its density is around 1.033-1.068 g/cm³. These properties are important for handling, storage, and reaction design. For instance, its flammability necessitates caution and adherence to safety protocols when used in industrial settings. The compound is miscible with many organic solvents, enhancing its utility in various reaction media. The purity of the product, often specified as ≥98.5% by GC analysis, is a critical factor for its effectiveness as an intermediate in sensitive synthetic processes.
The applications of 4-Chloro-2-butanone in synthesis are extensive. It serves as a key intermediate in the preparation of various pharmaceutical compounds, contributing to the development of APIs for a range of therapeutic areas. In the agrochemical sector, it is utilized to synthesize active ingredients for pesticides and herbicides, aiding in crop protection. Furthermore, its reactivity makes it valuable in the creation of specialty fine chemicals and heterocyclic compounds, opening avenues for innovation in materials science and beyond. When seeking to buy 4-Chloro-2-butanone, chemists and procurement managers often look for suppliers who can guarantee consistent quality and reliable supply.
Identifying a trustworthy manufacturer and supplier is key to ensuring the successful integration of 4-Chloro-2-butanone into your synthetic strategies. China-based companies, such as NINGBO INNO PHARMCHEM CO.,LTD., are prominent suppliers, offering high-purity grades of this intermediate. Their expertise in chemical manufacturing, coupled with competitive pricing and efficient export capabilities, makes them an attractive option for businesses worldwide. Sourcing from such a supplier ensures access to reliable product specifications, Certificates of Analysis (COA), and essential safety data, facilitating safe and effective use in your laboratory or production facility. Engaging with these suppliers provides an opportunity to discuss specific requirements, such as custom synthesis or specific purity grades.
In summary, 4-Chloro-2-butanone is a versatile and essential intermediate whose chemical properties facilitate critical synthesis applications. By understanding these properties and partnering with reliable manufacturers, chemical industry professionals can effectively leverage this compound to drive product development and innovation.
Perspectives & Insights
Data Seeker X
“The physicochemical properties of 4-Chloro-2-butanone are well-documented, typically including its appearance as a colorless to pale yellow liquid, a boiling point around 145-155°C, and a flash point of approximately 45.”
Chem Reader AI
“For instance, its flammability necessitates caution and adherence to safety protocols when used in industrial settings.”
Agile Vision 2025
“The compound is miscible with many organic solvents, enhancing its utility in various reaction media.”