Understanding the chemical properties of intermediates is fundamental to their effective utilization in synthesis. 5-Bromoacetyl Salicylamide, bearing the CAS number 73866-23-6, is a compound whose molecular structure and reactivity lend themselves to a variety of important chemical transformations. NINGBO INNO PHARMCHEM CO.,LTD., as a specialized supplier in China, is well-versed in these properties and their implications for pharmaceutical intermediate manufacturing and fine chemical production.

Chemically, 5-Bromoacetyl Salicylamide is characterized by its molecular formula C9H8BrNO3 and a molecular weight of approximately 258.07 g/mol. Its structure features an amide group, a hydroxyl group, and a bromoacetyl moiety, all attached to a benzene ring. This bromoacetyl group is particularly reactive, making it an excellent electrophile for nucleophilic substitution reactions. This reactivity is key to its function as a building block in complex organic synthesis.

The compound typically presents as a solid, often described as pale beige to brown, with a melting point generally reported in the range of 200-210°C, sometimes with decomposition. Its solubility characteristics in common solvents are important for reaction planning; it is often noted as slightly soluble in DMSO and methanol. These physical properties are critical data points for chemists when designing reaction conditions for pharmaceutical intermediate manufacturing or custom chemical synthesis.

The primary synthesis application for 5-Bromoacetyl Salicylamide is as a key intermediate in the production of Labetalol. The bromoacetyl group readily reacts with amine functionalities, facilitating the construction of the side chain necessary for Labetalol's pharmacological activity. This pathway is well-established in pharmaceutical intermediate manufacturing, ensuring a reliable route to this important medication.

Beyond its prominent role in Labetalol synthesis, 5-Bromoacetyl Salicylamide serves as a valuable precursor in various research and development settings. Its reactive functional groups allow for its incorporation into diverse molecular scaffolds, supporting the exploration of new chemical entities with potential therapeutic or industrial applications. For companies engaged in fine chemical production, it represents a versatile tool for creating novel compounds and materials.

At NINGBO INNO PHARMCHEM CO.,LTD., we ensure that our supply of 5-Bromoacetyl Salicylamide is characterized with precision. This attention to detail supports our clients in achieving reproducible results in their research and development projects and in their production of pharmaceutical reference standards. By providing high-quality intermediates, we aim to empower innovation across the chemical sciences.

In essence, the chemical properties of 5-Bromoacetyl Salicylamide make it a cornerstone intermediate for sophisticated synthesis. Its controlled reactivity and structural features are invaluable for pharmaceutical production and the broader landscape of fine chemical manufacturing, underscoring its importance in the chemical industry.