Understanding the chemical properties and application scope of key organic intermediates is vital for chemists and researchers aiming to optimize synthetic routes and develop novel materials. 1-Bromo-2-iodobenzene (CAS 583-55-1) is a compound that garners significant attention due to its versatile reactivity and its role as a precursor in numerous synthetic pathways. Typically appearing as a clear yellow liquid, this organohalogen compound presents unique opportunities for chemists seeking to build complex molecular architectures.

The physical and chemical properties of 1-Bromo-2-iodobenzene contribute to its widespread use. With a melting point around 9-10°C and a boiling point of 120-121°C at 15 mmHg, it is classified as a liquid under standard laboratory conditions. Its density is approximately 2.203 g/mL at 25°C, and its refractive index is around 1.661 (n20/D). Crucially, it is noted as being light-sensitive, necessitating careful storage and handling to maintain its purity and reactivity. While not readily soluble in water, it is miscible with common organic solvents, which is beneficial for its integration into various reaction media.

The primary application area for 1-Bromo-2-iodobenzene is as a building block in organic synthesis. Its dual halogenation allows for selective transformations, most famously in palladium-catalyzed cross-coupling reactions. The carbon-iodine bond’s higher reactivity compared to the carbon-bromine bond facilitates sequential reactions, a key advantage in constructing complex molecules. This makes it an ideal substrate for Suzuki, Stille, and Sonogashira couplings, reactions that are fundamental to producing pharmaceuticals, agrochemicals, and advanced materials. When purchasing this compound, buyers often seek a purity level of 99% or higher to ensure the success of these delicate catalytic processes.

Beyond coupling reactions, 1-Bromo-2-iodobenzene is used in the synthesis of diarylamines and other functionalized aromatic compounds. Its utility extends to materials science, where it can be incorporated into organic electronic materials or polymers. For researchers and industrial chemists looking to buy 1-Bromo-2-iodobenzene, partnering with reliable suppliers, especially manufacturers in China, can provide access to high-quality product at competitive prices. Understanding these properties and applications allows for more informed decisions when sourcing essential chemical intermediates for demanding projects.

In summary, the specific chemical properties of 1-Bromo-2-iodobenzene, including its light sensitivity and differential halogen reactivity, make it an invaluable intermediate. Its application scope, from pharmaceutical synthesis to materials science, highlights its versatility. Effective procurement involves selecting suppliers that can guarantee purity and consistency, ensuring the success of advanced synthetic endeavors.