For professionals in the pharmaceutical and fine chemical sectors, a deep understanding of the chemical properties and applications of key intermediates is crucial for successful product development and manufacturing. 2-Aminothiazol-4-acetic acid (CAS: 29676-71-9) is a compound that consistently demonstrates its value, particularly as an intermediate in the synthesis of advanced pharmaceutical agents.

Unpacking the Chemistry: Properties of 2-Aminothiazol-4-acetic Acid

2-Aminothiazol-4-acetic acid is characterized by its molecular formula C5H6N2O2S and a molecular weight of 158.18 g/mol. It typically presents as a white to off-white crystalline powder, indicating a relatively stable solid form that is manageable in industrial settings. Key physical properties include a melting point around 130°C (with decomposition) and solubility in water of 6.5 g/L at 20°C, along with solubility in DMSO. These characteristics are vital for R&D scientists and formulators when considering reaction conditions and formulation strategies.

The compound's structure features a thiazole ring with an amino group and an acetic acid side chain. This specific arrangement of functional groups makes it highly reactive and versatile for further chemical modifications. Its role as a precursor in complex organic syntheses is well-documented, making it a sought-after intermediate for manufacturers and researchers alike. When sourcing this compound, paying attention to these chemical properties ensures it will perform as expected in your synthesis pathways.

Critical Applications in Pharmaceutical Manufacturing

The primary application of 2-Aminothiazol-4-acetic acid lies in its role as a key intermediate for synthesizing cephalosporin antibiotics. These antibiotics are a cornerstone of modern antibacterial therapy, effective against a broad spectrum of pathogens. Specifically, it serves as a precursor for Cefotiam, a third-generation cephalosporin. The high purity and consistent quality of this intermediate are paramount for the efficacy and safety of the final drug product. Therefore, pharmaceutical companies looking to buy 2-Aminothiazol-4-acetic acid must partner with reliable manufacturers who can guarantee these standards.

Beyond its direct use in antibiotic synthesis, this compound may also find applications in other areas of fine chemical synthesis and research, contributing to the development of novel chemical entities. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of high-quality 2-Aminothiazol-4-acetic acid, supporting the pharmaceutical industry's needs for this critical intermediate. We provide detailed specifications and competitive pricing, ensuring our clients can confidently source this vital chemical.

In essence, 2-Aminothiazol-4-acetic acid is a fundamental building block whose chemical properties make it invaluable to the pharmaceutical industry. For procurement and R&D professionals, understanding these aspects and partnering with a reliable supplier like NINGBO INNO PHARMCHEM CO.,LTD. is key to successful and efficient drug manufacturing.