Understanding the fundamental chemical and physical properties of an intermediate is crucial for effective utilization in synthesis. 2-Fluoro-5-methylaniline, identified by CAS number 452-84-6, is a prime example of such a compound, offering a distinct combination of structural features valuable to organic chemists. As a supplier and manufacturer, we aim to provide comprehensive insights into this versatile aromatic amine, enabling our clients to make informed decisions when they purchase.

Physically, 2-Fluoro-5-methylaniline typically presents as a clear yellow to brown liquid. Its key properties include a boiling point range of 80-86°C at 11 mmHg, a density of approximately 1.109 g/mL at 25°C, and a refractive index of 1.533. These characteristics are important for handling, storage, and reaction design. For instance, its liquid state at room temperature simplifies measurement and addition in synthetic procedures. Knowing these physical attributes helps researchers and procurement specialists assess its suitability for their specific laboratory or industrial processes.

Chemically, the molecule features an amine group attached to a benzene ring, with a fluorine atom and a methyl group in specific positions. The amine group is nucleophilic and basic, readily participating in reactions such as acylation, alkylation, and salt formation. The electron-withdrawing nature of fluorine influences the reactivity of the aromatic ring and the basicity of the amine. This specific arrangement of substituents makes 2-Fluoro-5-methylaniline a valuable synthon in constructing more complex molecular architectures. Its utility as a chemical building block is recognized across various sectors.

The primary applications for 2-Fluoro-5-methylaniline lie in organic synthesis, particularly as an intermediate for pharmaceutical and agrochemical compounds. It serves as a critical starting material for creating molecules with desired biological activities. For example, it can be modified to form amide linkages, or its amine group can be diazotized for further transformations. Companies looking to procure this material often do so for research and development purposes or for the scaled-up production of active ingredients. The ability to buy high-purity 2-Fluoro-5-methylaniline from reliable China manufacturers ensures the success of these downstream processes.

In summary, 2-Fluoro-5-methylaniline (CAS 452-84-6) is more than just a chemical compound; it is a tool that enables chemical innovation. Its distinct physical and chemical properties, coupled with its widespread application in synthesis, make it a crucial intermediate. As a dedicated manufacturer, we are committed to supplying this essential chemical, offering quality and reliability to all our clients.