For chemists, R&D scientists, and product formulators, a deep understanding of chemical intermediates is crucial for innovation and efficient production. 2-Hydroxyphenylacetic Acid (CAS 614-75-5) is one such compound, valued for its specific chemical properties and its utility as a versatile intermediate. As a leading manufacturer and supplier, we aim to provide clarity on this important organic chemical.

Chemical Identity and Properties

2-Hydroxyphenylacetic Acid is an organic compound characterized by a phenylacetic acid structure with a hydroxyl group at the ortho position of the phenyl ring. Its chemical formula is C8H8O3, and it has a molecular weight of 152.15 g/mol. Typically, it presents as a yellow crystal powder, with a melting point range of 145-147°C, indicating its solid state at room temperature. Its solubility in methanol and water makes it amenable to various reaction conditions and purification methods.

The chemical structure, featuring both a carboxylic acid group and a phenolic hydroxyl group, makes it a reactive intermediate capable of undergoing esterification, etherification, and other condensation reactions. This dual functionality is key to its application in complex synthesis pathways. Understanding its pKa (around 4.17, predicted) can also be important for reactions involving acid-base catalysis.

Key Applications in Industry

The primary industrial applications for 2-Hydroxyphenylacetic Acid revolve around its role as a key intermediate. It is extensively used in:

  • Agrochemical Synthesis: It is a critical precursor in the manufacturing of azoxystrobin, a highly effective fungicide used globally to protect crops from a wide array of fungal diseases. The demand for such crop protection agents drives the need for reliable suppliers of this intermediate.
  • Pharmaceutical Synthesis: The compound is also an important intermediate in the synthesis of various pharmaceutical compounds, most notably atenolol, a beta-blocker used in cardiovascular medicine. Its consistent availability and purity are vital for pharmaceutical manufacturers.
  • Organic Synthesis: Beyond these major applications, it serves as a building block in broader organic chemistry research and the development of new specialty chemicals.

Sourcing and Quality Assurance

For procurement managers and R&D scientists, securing a consistent supply of high-purity 2-Hydroxyphenylacetic Acid (≥98%) from a trusted manufacturer is essential. When you buy this chemical, paying attention to the supplier's quality control measures, including the provision of a Certificate of Analysis (COA), is crucial. As a dedicated supplier in China, we ensure that our product meets rigorous standards. We offer competitive pricing and efficient logistics, making it easier for your company to purchase the quantities you need, whether for pilot-scale testing or large-scale production.

In conclusion, 2-Hydroxyphenylacetic Acid is a valuable chemical intermediate with well-defined properties and significant applications in the agrochemical and pharmaceutical industries. A thorough understanding of its chemical nature and a focus on sourcing from reliable manufacturers are key to leveraging its potential effectively in your research and production efforts.