6-Bromo-5-methylnicotinaldehyde, identified by its CAS number 885167-81-7, is a sophisticated organic compound that serves as a critical intermediate in chemical synthesis. Its molecular structure, C7H6BrNO, featuring a pyridine core with specific halogen and alkyl substituents along with an aldehyde functional group, lends it significant utility in complex chemical transformations. Understanding its chemical properties is fundamental for researchers and formulators aiming to leverage its potential in various applications, from pharmaceuticals to fine chemicals.

The compound's physical and chemical characteristics are well-defined, contributing to its value as a synthetic building block. It exhibits a molecular weight of 200.033. While a specific melting point isn't listed, its boiling point is approximated at 300.2±42.0 °C at 760 mmHg, and its density is around 1.6±0.1 g/cm³. Typically supplied with a purity of 97% minimum, it is available in solid form, making it manageable for laboratory and industrial use. The aldehyde group is highly reactive, readily participating in nucleophilic addition, oxidation, and reduction reactions. The bromine atom at the 6-position offers a site for cross-coupling reactions, such as Suzuki or Sonogashira couplings, while the methyl group at the 5-position can influence regioselectivity in further reactions. This combination of reactive sites makes 6-Bromo-5-methylnicotinaldehyde a highly versatile intermediate for chemists.

The applications of 6-Bromo-5-methylnicotinaldehyde are primarily centered around its role as a chemical intermediate. In the pharmaceutical industry, it is utilized in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing heterocyclic ring systems. Its structure is amenable to building complex molecular architectures required for novel drug candidates targeting a range of therapeutic areas. Beyond pharmaceuticals, it finds use in the development of agrochemicals, materials science research, and the synthesis of specialty organic compounds. The ability to buy this intermediate from reliable manufacturers, such as NINGBO INNO PHARMCHEM CO.,LTD., ensures that researchers and production facilities can access a consistent supply for their ongoing projects. When you need to purchase this chemical, inquire about bulk quantities to support larger scale synthesis needs.

For scientists and chemists involved in custom synthesis or developing new chemical entities, 6-Bromo-5-methylnicotinaldehyde offers a valuable starting point. Its well-defined reactivity and the availability of high-purity material from reputable Chinese suppliers mean that projects can move forward with confidence. Whether you are developing a new pharmaceutical drug or a specialty chemical, understanding the properties and potential of this intermediate is key to unlocking its full synthetic utility.