In the realm of specialized chemical synthesis, understanding the precise properties and diverse applications of intermediates is crucial for driving innovation. Benzofuran-6-carboxylic Acid (CAS 77095-51-3) is a compound that exemplifies this importance, serving as a versatile building block with significant implications in pharmaceutical development and organic chemistry. As NINGBO INNO PHARMCHEM CO.,LTD., a dedicated manufacturer and supplier, we aim to provide comprehensive insights into this valuable chemical.

Chemically, Benzofuran-6-carboxylic Acid possesses a molecular formula of C9H6O3 and a molecular weight of approximately 162.14 g/mol. Its structure features a fused benzofuran ring system with a carboxylic acid group attached at the 6-position. This arrangement imparts specific reactivity, making it an ideal candidate for various chemical transformations. The compound typically appears as a dark yellow solid, with a melting point often exceeding 182°C with decomposition, indicating good thermal stability under standard laboratory conditions. Solubility in common organic solvents like DMSO and methanol is often described as slight, which can influence its handling and reaction optimization in synthesis protocols. For researchers and procurement professionals, detailed specifications are readily available upon inquiry.

The primary applications of Benzofuran-6-carboxylic Acid are rooted in its role as a pharmaceutical intermediate. It is a critical reagent in the synthesis of SAR 118, a potent LFA-1/ICAM antagonist being developed for the treatment of dry eye syndrome. This specific application highlights the compound's importance in creating targeted therapies that address inflammatory conditions. Furthermore, it serves as a precursor for the synthesis of piperidinylpyrimidine derivatives, a class of compounds investigated for their inhibitory effects on HIV-1 LTR activation. These applications underscore its value in developing treatments for significant global health challenges. Manufacturers looking to buy this intermediate for pharmaceutical production can rely on our consistent quality.

Beyond its direct pharmaceutical intermediate roles, Benzofuran-6-carboxylic Acid is a useful tool in broader organic synthesis. Its functional groups allow for a range of reactions, including esterification, amidation, and further functionalization of the benzofuran ring. This versatility makes it a valuable component for chemists involved in creating novel molecular architectures for various research purposes, from materials science to agrochemicals. The availability of this compound from reliable suppliers like us facilitates such exploration, enabling chemists to efficiently build complex molecular scaffolds. We welcome requests for quotations to support your ongoing projects.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to being a premier supplier of Benzofuran-6-carboxylic Acid. Our manufacturing process is designed to ensure high purity and batch-to-batch consistency, meeting the rigorous demands of the pharmaceutical industry. We offer comprehensive support, including technical data and reliable logistics, to ensure your procurement needs are met efficiently. For any inquiries regarding pricing, availability, or custom synthesis requirements related to Benzofuran-6-carboxylic Acid, please do not hesitate to contact our dedicated sales team.