Understanding the detailed chemical properties of intermediates is crucial for efficient synthesis and application in the chemical and pharmaceutical industries. Diethyl 2,2-bis(hydroxymethyl)malonate, identified by CAS number 20605-01-0, is one such compound whose characteristics lend themselves to significant utility. This article delves into the chemical profile of this versatile molecule, from its appearance and solubility to its broader applications, providing valuable information for R&D scientists and formulators looking to buy or utilize this compound. As a leading chemical supplier and manufacturer, we are pleased to share this expertise.

Diethyl 2,2-bis(hydroxymethyl)malonate typically presents as a white to almost white crystalline solid, a key visual indicator of its purity and form. Its molecular formula, C9H16O6, translates to a molecular weight of approximately 220.22 g/mol. The compound exhibits limited solubility in water, a characteristic that often guides its handling and reaction conditions in various synthetic processes. Its melting point, commonly cited around 49-51°C, further aids in its identification and quality assessment. These physical attributes are essential for formulators and researchers to consider when planning their chemical syntheses.

The synthesis of Diethyl 2,2-bis(hydroxymethyl)malonate typically involves the reaction of diethyl malonate with formaldehyde, often under specific catalytic conditions. Sources indicate that this reaction can be carried out efficiently, yielding the desired product with high purity. For professionals seeking to buy this chemical, understanding the typical synthesis routes can provide confidence in the material's origin and manufacturing process. The availability of this intermediate from reliable manufacturers in China ensures that global clients can access it for their diverse chemical needs.

The applications of Diethyl 2,2-bis(hydroxymethyl)malonate are diverse and impactful. Its primary recognized use is as a critical intermediate in the pharmaceutical sector, particularly for the synthesis of antiviral agents such as acyclovir and ganciclovir. These drugs are vital in treating a range of viral infections, making the reliable supply of Diethyl 2,2-bis(hydroxymethyl)malonate essential for public health. Furthermore, its chemical structure makes it an excellent reagent for broader organic synthesis. It can be utilized in the preparation of substituted malonic esters, acrylic esters, and isobutyric esters, as well as in the creation of dienophiles and other complex organic molecules. This versatility positions it as a valuable tool for chemists in research and development, enabling the creation of novel materials and compounds.

For businesses looking to purchase Diethyl 2,2-bis(hydroxymethyl)malonate, partnering with a reputable manufacturer is paramount. We, as a dedicated chemical supplier, offer this product with guaranteed quality and specifications. Our commitment extends to providing comprehensive technical support and efficient procurement solutions. Whether you are involved in pharmaceutical R&D, fine chemical manufacturing, or other specialized chemical applications, ensuring a consistent supply of high-quality Diethyl 2,2-bis(hydroxymethyl)malonate is key. We encourage you to explore our offerings and discover how we can support your chemical sourcing requirements from China.