1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a synthetic phospholipid that has garnered significant attention across various scientific disciplines due to its versatile chemical properties and extensive applications. As a specialist supplier of high-quality biochemicals, NINGBO INNO PHARMCHEM CO.,LTD. is proud to offer DOPE and shed light on its importance in research and development.

Chemically, DOPE is a diacylphosphatidylethanolamine, meaning it consists of a glycerol backbone esterified with two oleic acid (18:1) fatty acid chains at the sn-1 and sn-2 positions, and a phosphoethanolamine headgroup at the sn-3 position. This structure imparts unique characteristics, including its ability to form stable lipid bilayers and its susceptibility to forming hexagonal phases under certain conditions. This phase behavior is particularly relevant in its use in liposome and nanoparticle formulations. The molecule's composition makes it soluble in organic solvents such as chloroform and methanol, which are commonly used in lipid preparation and formulation.

The applications of DOPE are remarkably diverse, spanning critical areas such as drug delivery systems, vaccine development, and cell biology. In drug delivery, DOPE is frequently used as a component of liposomes and lipid nanoparticles to enhance membrane fluidity and stability, thereby improving the encapsulation and controlled release of therapeutic agents. Its ability to interact with cellular membranes also makes it valuable for gene therapy, where it aids in the transfection of nucleic acids into target cells, often in conjunction with cationic lipids. Researchers frequently seek to buy DOPE for studying membrane dynamics and for creating model systems that mimic biological membranes.

For those looking to purchase DOPE, selecting a reliable manufacturer and supplier is paramount. The purity of the lipid directly influences the success of the application. NINGBO INNO PHARMCHEM CO.,LTD. ensures that our DOPE is supplied at high purity levels (≥98%), making it suitable for advanced research and development projects. We are a key manufacturer and supplier in China, committed to providing consistent quality and competitive pricing to researchers globally. Procuring DOPE from a trusted source guarantees that your formulations will exhibit predictable behavior and achieve desired outcomes.

In summary, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a chemically versatile phospholipid with indispensable applications in modern scientific research. We encourage researchers and developers to consider NINGBO INNO PHARMCHEM CO.,LTD. as their preferred supplier for high-quality DOPE, supporting innovation across pharmaceuticals, biotechnology, and beyond.