Understanding the fundamental chemical properties of a compound is crucial for its effective application in various scientific and industrial fields. Quinuclidine, identified by its CAS Number 100-76-5, is a fascinating bicyclic amine that has garnered significant attention for its unique structural characteristics and its utility as a building block and catalyst. For chemists, researchers, and procurement specialists seeking high-quality chemical intermediates, a thorough grasp of Quinuclidine's attributes and applications is invaluable. This article explores these aspects and highlights the importance of sourcing from reliable manufacturers.

Quinuclidine, with the molecular formula C7H13N and a molecular weight of 111.18 g/mol, possesses a rigid, cage-like structure known as 1-Azabicyclo[2.2.2]octane. This conformation imparts distinct chemical behaviors. It is a relatively strong organic base, with the conjugate acid exhibiting a pKa of approximately 11.0, making it effective in promoting certain reactions where a strong, sterically accessible base is required. Physically, Quinuclidine typically presents as a white to pale yellow crystalline powder, with a melting point in the range of 157-160°C. Its unique structure also leads to interesting conformational properties, with the internal methylene hydrogens being eclipsed and the fused cyclohexane rings adopting boat conformations.

The applications of Quinuclidine are diverse and span multiple industries. In the pharmaceutical sector, it serves as a vital intermediate for the synthesis of various Active Pharmaceutical Ingredients (APIs). Its bicyclic framework is a common motif in many biologically active molecules, contributing to receptor binding and pharmacological efficacy. For researchers looking to buy Quinuclidine for medicinal chemistry, its purity is paramount, with typical specifications requiring a minimum of 97%. Beyond pharmaceuticals, Quinuclidine finds application in the development of advanced materials, particularly in the field of Organic Light-Emitting Diodes (OLEDs). Its electronic properties can be fine-tuned within organic semiconductors to enhance charge transport and emission characteristics.

Furthermore, Quinuclidine is recognized as a useful catalyst in various organic transformations. Its basicity and structure allow it to participate effectively in reactions such as the Baylis-Hillman reaction, where it has been identified as an optimum catalyst. For researchers exploring new synthetic methodologies, sourcing high-purity Quinuclidine from a dependable manufacturer is essential for reproducible results. When considering purchase, companies often look for suppliers in China that offer competitive pricing for this specialized chemical, ensuring a balance between cost and quality.

In summary, Quinuclidine (CAS 100-76-5) is a compound of significant chemical interest and industrial utility. Its strong basicity, unique bicyclic structure, and high purity make it an indispensable intermediate in pharmaceuticals and a valuable material in OLED technology, as well as a competent catalyst. For those seeking to purchase Quinuclidine, partnering with experienced manufacturers ensures access to high-quality products that drive innovation across these critical sectors.