Understanding the detailed chemical properties of key intermediates is fundamental for successful pharmaceutical development. (S)-Tert-Butyl 3-Oxo-1-Phenylpropylcarbamate, identified by CAS 135865-78-0, is a molecule of significant interest due to its role in synthesizing advanced pharmaceutical agents. Its physical form is typically a white to off-white crystalline powder, indicating a degree of purity essential for its intended applications.

Chemically, this compound features a protected amine group (tert-butoxycarbonyl or Boc) and a ketone, attached to a chiral center bearing a phenyl group. This combination of functional groups makes it a versatile precursor in organic synthesis. Its utility is particularly noted in the production of spirotropane derivatives, which are being investigated for their therapeutic effects on CCR5 chemokine receptors. These receptors are implicated in various disease states, including HIV infection, and the development of compounds that modulate them is a major area of pharmaceutical research.

The synthesis pathways for (S)-Tert-Butyl 3-Oxo-1-Phenylpropylcarbamate itself are critical for ensuring its quality. Researchers often employ asymmetric synthesis techniques to achieve the desired enantiomeric form, as chirality plays a crucial role in drug activity. As a Maraviroc intermediate, its chemical integrity directly impacts the final API. For any research or manufacturing endeavor requiring this compound, understanding its solubility in common organic solvents, its stability under various storage conditions (sealed, cool, and dry), and its reactivity is key to optimizing synthetic processes and achieving high-quality end products.