The Chemical Properties and Applications of Trimethylene Carbonate (CAS 2453-03-4)
Trimethylene Carbonate (TMC), chemically known as 1,3-Dioxan-2-one, with the CAS number 2453-03-4, is a cyclic carbonate ester that holds significant importance in the field of polymer chemistry, particularly for creating biodegradable and biocompatible materials. Understanding its chemical properties is fundamental for researchers and manufacturers looking to leverage its capabilities for advanced applications.
Chemically, TMC is a six-membered ring structure containing an ester group. Its molecular formula is C4H6O3, and it has a molecular weight of 102.09 g/mol. As observed from various sources, including leading chemical suppliers, TMC typically presents as a white, crystalline solid. Its melting point is generally in the range of 45-48°C, indicating it can be a low-melting solid under ambient or slightly elevated temperatures. This characteristic can be advantageous during processing and polymerization reactions.
A key aspect of TMC's utility lies in its reactivity. It undergoes ring-opening polymerization (ROP) through anionic, cationic, or coordination-insertion mechanisms. This process allows it to form long polymer chains, most notably poly(trimethylene carbonate) (PTMC). PTMC is highly valued for its biocompatibility, biodegradability, and flexibility. These properties stem from the ester linkages in its backbone, which can be hydrolyzed by biological systems. The degradation products are generally non-toxic, making TMC an attractive monomer for medical applications.
The applications for Trimethylene Carbonate are diverse and growing. In the biomedical industry, it is widely used to synthesize polymers for drug delivery systems, where the polymer matrix controls the release rate of therapeutic agents. It is also integral to the production of bioabsorbable medical devices such as surgical sutures, bone screws, and tissue engineering scaffolds. The ability to tailor the polymer's properties by copolymerizing TMC with other monomers like lactide or caprolactone further enhances its versatility.
For procurement managers and research scientists aiming to buy Trimethylene Carbonate, seeking out a reliable manufacturer that guarantees high purity (>99%) is crucial for successful polymerization outcomes. Working with a trusted supplier ensures the consistency and quality necessary for these demanding applications. Whether you are synthesizing novel polymers or developing advanced biomedical products, understanding the chemical nature and potential of Trimethylene Carbonate is the first step towards innovation.
Perspectives & Insights
Silicon Analyst 88
“PTMC is highly valued for its biocompatibility, biodegradability, and flexibility.”
Quantum Seeker Pro
“These properties stem from the ester linkages in its backbone, which can be hydrolyzed by biological systems.”
Bio Reader 7
“The degradation products are generally non-toxic, making TMC an attractive monomer for medical applications.”