For professionals in the chemical and pharmaceutical industries, a deep understanding of a compound's properties is fundamental to its effective application and procurement. Beta-(4-Chlorophenyl) Glutaric Anhydride, a specialized organic chemical, is no exception. Known by its CAS number 182955-12-0, this compound is primarily utilized as a key intermediate in synthesis. This article delves into its essential physical and chemical properties, providing crucial information for buyers and researchers looking to purchase or utilize this material.

The chemical identity of Beta-(4-Chlorophenyl) Glutaric Anhydride is clearly defined by its molecular formula, C11H9ClO3, and a molecular weight of approximately 224.64 g/mol. Its structure features a glutaric anhydride core substituted with a 4-chlorophenyl group. This specific arrangement of atoms dictates its reactivity and its utility in chemical synthesis. When sourcing this compound, one of the primary specifications that buyers will look for is its appearance. Beta-(4-Chlorophenyl) Glutaric Anhydride is typically supplied as a white crystalline powder, indicating a high degree of purity and a well-defined solid state.

Further physical properties relevant to its handling and application include its density, which is 1.348 g/cm³, and its boiling point of 393.2 °C at atmospheric pressure. The flash point of 176 °C suggests that it is not highly flammable under normal conditions, but standard laboratory safety precautions should always be observed. Its vapor pressure is quite low at 2.17E-06 mmHg at 25 °C, meaning it is not significantly volatile. These properties are vital for assessing storage conditions, potential exposure risks, and compatibility with various processing environments.

The assay of Beta-(4-Chlorophenyl) Glutaric Anhydride is typically specified as ≥98.0%. This high purity is critical for its primary role as an intermediate in pharmaceutical synthesis, most notably in the production of Baclofen (CAS: 1134-47-0). Impurities can lead to reduced yields, unwanted side reactions, and contamination of the final product, which is unacceptable in pharmaceutical manufacturing. Therefore, when seeking to buy this compound, buyers should always request Certificates of Analysis (CoA) from the manufacturer that confirm the assay and detail any significant impurities.

In conclusion, Beta-(4-Chlorophenyl) Glutaric Anhydride possesses a set of well-defined physical and chemical properties that make it a valuable intermediate. Its appearance as a white crystalline powder, high assay of ≥98.0%, and specific density and boiling points are key attributes for procurement. Understanding these characteristics is essential for R&D scientists and purchasing managers to effectively source and utilize this compound in their synthesis processes. When considering a purchase, always confirm these specifications with your chosen manufacturer or supplier.