The efficacy of modern antibiotics, such as cefdinir, is intrinsically linked to the quality and specific properties of the chemical intermediates used in their synthesis. S-2-Benzothiazolyl (Z)-2-(2-aminothiazol-4-yl)-2-acetyloxyiminothioacetate, identified by its CAS Number 104797-47-9, stands out as a critical component in the production of this important third-generation cephalosporin antibiotic. Understanding its detailed chemical and physical properties is essential for any pharmaceutical manufacturer aiming for optimal synthesis outcomes.

This vital intermediate typically presents as a white crystalline powder. Its molecular formula is C14H10N4O3S3, and it possesses a molecular weight of approximately 378.45 g/mol. The compound's structure integrates a benzothiazole ring system linked to a 2-aminothiazole moiety via a thioacetate ester linkage. This specific chemical architecture imbues it with the necessary reactivity and stability for its role in cefdinir synthesis. Key physical properties often cited include a density of around 1.667 g/cm³ and a high flash point of approximately 315.964°C, indicating its relative stability under standard handling conditions. These characteristics are vital for safety during processing and storage, especially when dealing with large quantities. For manufacturers looking to buy this intermediate, these specifications are critical for process validation.

The purity of the intermediate is a paramount concern for pharmaceutical manufacturers. S-2-Benzothiazolyl (Z)-2-(2-aminothiazol-4-yl)-2-acetyloxyiminothioacetate is generally supplied with a purity of ≥98.0%. This high level of purity is indispensable for ensuring that the subsequent synthesis steps for cefdinir proceed efficiently, minimizing the formation of unwanted by-products and impurities. Pharmaceutical companies that purchase this intermediate rely on this assurance to meet regulatory standards and ensure the final API’s quality and safety. When sourcing, always confirm the purity specifications with your chosen supplier or manufacturer.

The synthesis of cefdinir involves precise chemical reactions where the thioacetate group plays a crucial role in forming the amide bond essential for the antibiotic's activity. The reliable performance of this intermediate is directly tied to its structural integrity and purity. Therefore, choosing a reputable manufacturer, especially one located in China known for its chemical production capabilities, is a sound strategy. Companies can obtain competitive price points and consistent quality by engaging with well-established suppliers who provide comprehensive technical data and support. Packaging typically involves 25 kg drums, ensuring the compound’s stability during transit and storage.

In conclusion, a thorough understanding of the chemical and physical properties of S-2-Benzothiazolyl (Z)-2-(2-aminothiazol-4-yl)-2-acetyloxyiminothioacetate is fundamental for pharmaceutical manufacturers. Its high purity, specific molecular structure, and physical characteristics make it a cornerstone for cefdinir production. By carefully selecting a trusted supplier and confirming these essential specifications, manufacturers can ensure the successful and efficient synthesis of this critical antibiotic.