For chemists and pharmaceutical manufacturers, a thorough understanding of chemical intermediates is fundamental to successful synthesis. Ethyl 4-Hydroxypiperidine-1-carboxylate, identified by CAS number 65214-82-6, is a crucial compound in this regard. This article delves into its essential chemical and physical properties, providing valuable insights for professionals seeking to purchase or utilize this intermediate.

Ethyl 4-Hydroxypiperidine-1-carboxylate, with the molecular formula C8H15NO3 and a molecular weight of approximately 173.21 g/mol, is recognized for its utility as a pharmaceutical intermediate. Physically, it typically presents as a pale yellow liquid. Its structural features include a six-membered piperidine ring, a hydroxyl group at the 4-position, and an N-ethoxycarbonyl group. These functional groups dictate its reactivity and suitability for various synthetic transformations.

Key chemical properties that are important for synthesis planning include its boiling point, density, and flash point. Data indicates a boiling point of around 275.1 °C at 760 mmHg and a density of approximately 1.165 g/cm³. The flash point is reported to be around 120.2 °C. These parameters are critical for understanding handling, storage, and reaction conditions. The compound's solubility and stability in common organic solvents are also vital considerations for researchers and formulators who plan to buy this chemical for their processes.

The compound's role as an intermediate, particularly in the synthesis of drugs like Bepotastine besilate, highlights its importance in the pharmaceutical supply chain. The presence of the secondary alcohol and the carbamate ester allows for diverse chemical reactions, such as esterification, etherification, or cleavage, enabling the construction of complex molecular architectures. As a reputable manufacturer and supplier, we ensure that our Ethyl 4-Hydroxypiperidine-1-carboxylate meets precise specifications, providing R&D scientists and procurement managers with a reliable source for their synthetic needs.

Understanding these chemical properties is crucial for anyone looking to procure or work with Ethyl 4-Hydroxypiperidine-1-carboxylate. Our commitment as a supplier is to provide high-quality intermediates that facilitate your research and manufacturing objectives, ensuring consistency and reliability in every batch.