For professionals in the chemical and pharmaceutical sectors, a thorough understanding of a compound's chemical properties is fundamental to successful sourcing, application, and synthesis. L-Valine Methyl Ester Hydrochloride (H-Val-OMe HCl), identified by CAS number 6306-52-1, is a crucial amino acid derivative whose properties dictate its utility and performance in various industrial processes. This guide aims to illuminate these key characteristics for buyers and researchers.

The molecular formula of H-Val-OMe HCl is C6H14ClNO2, with a molecular weight of approximately 167.63 g/mol. This relatively small molecule is derived from the natural amino acid L-valine, featuring an esterified carboxyl group (methyl ester) and presented as a hydrochloride salt. The presence of the hydrochloride salt enhances its solubility in polar solvents, particularly water, making it easier to handle and react in aqueous or semi-aqueous systems. This solubility is a critical factor for many chemical synthesis processes.

A key physical characteristic for buyers is its appearance, which is typically described as a white to off-white crystalline powder. The crystalline nature indicates a well-defined structure, and the color is indicative of its purity. Manufacturers often provide specifications regarding the consistency of this appearance. The melting point is another important specification, commonly reported in the range of 171-173 °C (with literature values noting 'lit.', suggesting a literature-reported value). A sharp melting point within this narrow range is a good indicator of high purity and consistent batch quality.

The chirality of H-Val-OMe HCl is also noteworthy. As it is derived from L-valine, it possesses a chiral center, and its specific rotation ([α]20/D) is typically measured, often falling within the range of +15.5° to +16.5° (measured in water at a specific concentration). This optical activity is critical for applications where stereochemistry is important, such as in the synthesis of chiral drugs or peptides, ensuring the correct enantiomer is used.

When considering bulk purchases or critical synthesis, buyers should pay close attention to purity specifications. Beyond the assay percentage (often stated as ≥99.0%), understanding the levels of impurities is vital. These can include other amino acids, residual solvents, or byproducts from the synthesis. Reputable suppliers will offer detailed impurity profiling, often determined by techniques like HPLC or GC. Parameters like 'Loss on Drying' (LOD) and 'Residue on Ignition' (ROI) also provide insights into the presence of volatile components or inorganic residues, respectively.

Understanding these chemical and physical properties allows procurement managers and R&D scientists to make informed decisions when sourcing H-Val-OMe HCl. It ensures that the material procured aligns with the specific requirements of their applications, whether for pharmaceutical intermediate synthesis, peptide chemistry, or other fine chemical processes. We, as a leading manufacturer, are committed to providing H-Val-OMe HCl that meets these stringent quality standards, ensuring reliable performance and consistent results for our customers.