For professionals in the chemical industry, a thorough understanding of a compound's properties and safe handling procedures is fundamental. 2,6-Dichloroacetophenone (CAS 2040-05-3) is a key intermediate in various synthesis processes, and knowledge of its characteristics ensures efficient and safe utilization. This article delves into the physical and chemical properties, as well as the recommended handling and storage protocols for this important compound.

Physical and Chemical Properties of 2,6-Dichloroacetophenone

2,6-Dichloroacetophenone is typically presented as a white crystalline solid. Key properties include:

  • CAS Number: 2040-05-3
  • Molecular Formula: C8H6Cl2O
  • Molecular Weight: 189.04 g/mol
  • Appearance: White Powder / Crystal
  • Purity: Typically ≥98% (GC)
  • Melting Point: 37-41 °C (literature value)
  • Boiling Point: Approximately 176-180 °C at 83 mmHg, or 208 °C at 760 mmHg.
  • Solubility: Insoluble in water, soluble in organic solvents.
  • Density: Approximately 1.304 g/cm³
  • Flash Point: Typically above 230 °F (>110 °C), indicating it is not highly flammable.

These properties are essential for process design, formulation, and safety assessments. As a manufacturer or supplier, providing accurate specifications is a mark of professionalism.

Hazard Identification and Safety Precautions

According to GHS classification, 2,6-Dichloroacetophenone is often labeled with hazard statements such as H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Therefore, appropriate safety measures must be taken:

  • Personal Protective Equipment (PPE): Always wear appropriate PPE, including safety glasses with side-shields, chemical-resistant gloves (e.g., nitrile rubber), and protective clothing. If dust is generated, a dust mask (e.g., N95) or respirator may be necessary.
  • Handling: Avoid contact with skin, eyes, and clothing. Prevent the generation of dust and aerosols. Handle in a well-ventilated area, preferably under a fume hood. Wash hands thoroughly after handling.
  • Inhalation: Avoid breathing dust, fumes, mist, or gas. Ensure adequate ventilation to keep airborne concentrations low.

Storage Recommendations

Proper storage is crucial to maintain the quality and stability of 2,6-Dichloroacetophenone:

  • Container: Keep containers tightly closed.
  • Environment: Store in a dry, cool, and well-ventilated place, away from incompatible materials such as strong oxidizing agents.
  • Temperature: Store at room temperature or as recommended by the supplier.

Where to Buy Quality 2,6-Dichloroacetophenone

When you purchase 2,6-Dichloroacetophenone, especially in bulk, it is vital to choose a reputable supplier or manufacturer. Look for companies that provide comprehensive Safety Data Sheets (SDS) and adhere to international quality standards. Companies that clearly list product specifications, including purity and handling guidelines, are usually a good indication of their commitment to quality.

Conclusion

Understanding the physical, chemical, and safety aspects of 2,6-Dichloroacetophenone (CAS 2040-05-3) is fundamental for its effective and safe use in synthesis. By adhering to proper handling, storage, and personal protection guidelines, and by sourcing from reliable suppliers, R&D professionals and procurement managers can ensure successful outcomes in their projects. Always refer to the latest SDS for the most up-to-date safety information when working with this or any chemical.