For chemists, formulators, and procurement specialists in the chemical industry, a thorough understanding of a compound's properties is vital for its effective and safe utilization. 2-Chloroacetophenone, identified by its CAS number 532-27-4, is a significant intermediate chemical with specific characteristics that dictate its applications and handling requirements. NINGBO INNO PHARMCHEM CO.,LTD., as a leading manufacturer and supplier, emphasizes the importance of this knowledge for all our partners.

Chemical and Physical Properties of 2-Chloroacetophenone

2-Chloroacetophenone (Molecular Formula: C8H7ClO, Molecular Weight: 154.59) typically presents as a white or light yellow crystalline solid. Its melting point ranges between 54-56°C, and it has a boiling point of approximately 244-245°C. A key characteristic relevant to its use in synthesis is its solubility profile: it is insoluble in water but readily soluble in common organic solvents such as ether, ethanol, chloroform, and benzene. This solubility makes it amenable to a wide range of reaction conditions and purification methods. Our commitment as a supplier is to provide material that consistently meets these established specifications.

Applications and Reactivity in Synthesis

The chemical reactivity of 2-Chloroacetophenone stems from its structure, featuring a reactive alpha-chloro ketone group. This makes it an excellent electrophile for nucleophilic substitution reactions. Its primary applications include serving as a building block in the synthesis of agrochemicals, pharmaceuticals, and various other fine chemicals. Researchers and industrial chemists frequently buy 2-Chloroacetophenone for its ability to introduce the phenacyl moiety into target molecules, facilitating the creation of diverse and complex chemical structures.

Safe Handling and Storage Practices

Given its nature as a chemical intermediate, proper handling and storage of 2-Chloroacetophenone (CAS 532-27-4) are crucial for safety and maintaining product integrity. It is advisable to consult the Material Safety Data Sheet (MSDS) provided by the manufacturer for detailed guidelines. General precautions include:

  • Personal Protective Equipment (PPE): Always use appropriate PPE, such as gloves, eye protection, and lab coats, to prevent skin and eye contact.
  • Ventilation: Handle in a well-ventilated area or fume hood to avoid inhalation of dust or vapors.
  • Storage: Store in a tightly closed container in a cool, dry place, away from incompatible materials.
  • Disposal: Follow local regulations for proper chemical waste disposal.

NINGBO INNO PHARMCHEM CO.,LTD. provides comprehensive SDS and COA to support safe and effective use of our 2-Chloroacetophenone. As your trusted chemical supplier, we encourage you to reach out for any further technical information or assistance regarding product handling and application.