Understanding the chemical properties and proper handling of specialized reagents is fundamental for successful research and manufacturing. 5-Indolylboronic acid (CAS 144104-59-6) is a compound that, while immensely useful, requires careful consideration of its characteristics. As a vital pharmaceutical intermediate and building block in organic synthesis, knowing its properties ensures optimal utilization and safety.

Chemically, 5-Indolylboronic acid possesses the molecular formula C8H8BNO2 and a molecular weight of approximately 160.97 g/mol. Its physical appearance is typically a white crystalline powder. A significant characteristic noted across its specifications is its sensitivity to air. This air sensitivity means that prolonged exposure can lead to degradation, impacting its reactivity and the purity of subsequent reactions. Therefore, proper storage and handling are crucial. Keeping the compound sealed in a dry environment, ideally under an inert atmosphere like nitrogen or argon, and storing it at recommended temperatures (often 0-6°C or room temperature depending on the specific grade and supplier) is vital to maintain its integrity.

For researchers and manufacturers sourcing 5-Indolylboronic acid, attention to these details is paramount. NINGBO INNO PHARMCHEM CO.,LTD. provides this essential intermediate and emphasizes the importance of adhering to recommended storage and handling protocols. This diligence ensures that the compound retains its high purity and reactivity, crucial for achieving consistent results in demanding applications such as Suzuki-Miyaura cross-coupling reactions.

The melting point of 5-Indolylboronic acid is reported to be in the range of 170-175 °C. This thermal property, along with its solubility characteristics (often limited in water but soluble in certain organic solvents), informs its application in various reaction media. When planning synthetic routes, understanding these physical and chemical attributes allows chemists to select appropriate solvents, reaction temperatures, and work-up procedures.

Safety is also a key consideration. While specific hazard statements may vary slightly between suppliers, compounds like 5-Indolylboronic acid are generally classified with warnings regarding skin irritation, eye irritation, and respiratory irritation. Standard laboratory safety practices, including the use of personal protective equipment (PPE) such as gloves, safety glasses, and lab coats, are essential. Working in a well-ventilated area or a fume hood is also recommended to minimize exposure to airborne particles.

By carefully understanding and respecting the chemical properties and handling requirements of 5-Indolylboronic acid, researchers and manufacturers can effectively leverage its potential in driving innovation. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying this critical chemical with the necessary information to ensure its safe and successful application in scientific endeavors.