Methyl 4-(bromomethyl)benzoate (CAS 2417-72-3) is a fine chemical widely used as an intermediate in various industrial processes, particularly in pharmaceutical synthesis. For procurement professionals and chemical engineers, a thorough understanding of its chemical properties, handling procedures, and safety considerations is crucial for efficient and safe operations. This overview, provided by experienced manufacturers and suppliers, aims to equip you with essential knowledge.

Key Chemical Properties and Specifications

Methyl 4-(bromomethyl)benzoate possesses a distinct set of physical and chemical properties that dictate its applications and handling:

  • Molecular Formula: C9H9BrO2
  • Molecular Weight: 229.07 g/mol
  • Appearance: Typically presented as a white to off-white crystalline powder.
  • Melting Point: Approximately 57-58 °C (lit.), indicating it is a solid at room temperature.
  • Boiling Point: Around 130-135 °C at 2 mm Hg (lit.).
  • Purity: High purity grades (≥99%) are commonly available from reputable suppliers, which is essential for sensitive applications like API manufacturing.
  • Solubility: Soluble in organic solvents such as chloroform and methanol, with low solubility in water.

Safety and Handling Precautions

As a reactive chemical intermediate, Methyl 4-(bromomethyl)benzoate requires careful handling and adherence to safety protocols. It is known to be a lachrymator, meaning it can cause irritation to the eyes and respiratory tract.

  • Personal Protective Equipment (PPE): Always wear appropriate PPE, including chemical-resistant gloves, safety goggles with side shields, and protective clothing when handling this substance. In well-ventilated areas or when there's a risk of dust or vapor formation, respiratory protection should be used.
  • Storage Conditions: Store in a cool, dry, and well-ventilated container, away from direct sunlight, heat, and incompatible materials. Keeping it in a tightly closed container under inert gas (like nitrogen or argon) is recommended, especially for long-term storage, to maintain stability.
  • Handling Procedures: Avoid dust formation and inhalation. Use in a fume hood or a well-ventilated area. Ensure proper grounding to prevent static discharge.
  • First Aid Measures: In case of contact, immediately flush eyes or skin with plenty of water. If inhaled, move to fresh air. Seek medical attention if irritation persists or if symptoms are severe.

Procuring Methyl 4-(bromomethyl)benzoate

When seeking to buy Methyl 4-(bromomethyl)benzoate, prioritize suppliers who can provide detailed safety data sheets (SDS) and clear handling instructions. Manufacturers in China offer competitive pricing for this chemical, making it an attractive option for global procurement. Always ensure your supplier has robust quality control systems in place to guarantee the specified purity and consistency.

By adhering to these guidelines, industrial users can safely and effectively utilize Methyl 4-(bromomethyl)benzoate in their manufacturing processes, leveraging its chemical versatility while minimizing risks.