For professionals in chemical synthesis and research, a thorough understanding of the properties and safe handling of key reagents is paramount. N-(p-Toluenesulfonyl)-3-pyrroline, identified by CAS number 16851-72-2, is a significant heterocyclic intermediate whose chemical characteristics dictate its utility and require careful management.

Physically, this compound typically presents as a white to almost white crystalline powder. This solid form is advantageous for accurate weighing and controlled addition in chemical reactions. Its melting point, often cited around 127°C, is a key parameter for quality control. While specific solubility data can vary, it is generally soluble in common organic solvents, facilitating its use in solution-phase chemistry. The purity, frequently specified as 98.0% or higher, ensures that researchers can rely on it for reproducible synthetic outcomes.

From a chemical reactivity standpoint, the p-toluenesulfonyl group attached to the pyrroline ring imparts specific electronic properties. This functionalization makes it a valuable substrate for various organic transformations. As a heterocyclic compound, it can participate in reactions common to pyrrolines, while the sulfonyl group can influence reactivity or serve as a leaving group or protecting group in certain contexts. Its utility as a building block in organic synthesis, particularly for creating complex molecular structures and pharmaceutical intermediates, underscores its importance.

Safe handling and storage are crucial. N-(p-Toluenesulfonyl)-3-pyrroline requires storage in a cool, dry, and well-ventilated place, often in tightly closed containers to prevent moisture absorption or degradation. Standard laboratory personal protective equipment (PPE), including gloves, safety glasses, and lab coats, should be worn when handling this chemical. While not typically classified as highly hazardous, appropriate precautions should always be taken, as indicated by its Safety Data Sheet (SDS).

For those looking to buy N-(p-Toluenesulfonyl)-3-pyrroline, identifying a reliable supplier is essential. Whether you are a researcher needing small quantities or a company requiring bulk orders, a reputable manufacturer will provide the necessary purity, technical data, and competitive pricing. When you purchase this intermediate, ensure your chosen vendor can offer consistent quality and timely delivery to support your ongoing projects in chemical R&D and manufacturing.