In the intricate world of chemical synthesis, understanding the properties and applications of key intermediates is fundamental to driving innovation and efficiency. 4-Hydroxy-2-quinolone, identified by its CAS number 86-95-3, is one such compound that merits close attention from R&D professionals and procurement specialists. This article explores the chemical profile and industrial relevance of this versatile heterocyclic molecule.

Chemical Characteristics of 4-Hydroxy-2-quinolone

4-Hydroxy-2-quinolone, also known by synonyms such as 2,4-Quinolinediol or 4-hydroxy-2-quinolone, is an organic compound belonging to the quinoline family. Its molecular formula is C9H7NO2, and it has a molecular weight of 161.16 g/mol. Typically presented as a light brown powder, its key chemical feature is the presence of a hydroxyl group at the 4-position and a keto group at the 2-position of the quinoline ring. This dual functionality makes it highly reactive and suitable for a variety of chemical transformations. The compound's melting point is generally reported to be above 300°C, indicating significant thermal stability.

Industrial Applications: A Focus on Pharmaceuticals

The predominant industrial application for 4-Hydroxy-2-quinolone is its role as a crucial intermediate in the synthesis of pharmaceuticals. The quinoline scaffold is a privileged structure in medicinal chemistry, appearing in a wide range of drugs with diverse therapeutic activities. As a result, pharmaceutical companies frequently seek to buy 4-hydroxy-2-quinolone as a starting material or key building block for developing novel APIs or for the efficient synthesis of existing drug molecules. Its specific structure allows for tailored derivatization, enabling the creation of compounds with targeted biological efficacy.

While pharmaceuticals are its main domain, the compound's structure might also find niche applications in the synthesis of specialized dyes or as a research chemical in advanced organic synthesis projects. Researchers might also be interested in its potential role in materials science, although these applications are less common.

Sourcing and Procurement Insights

For businesses needing to purchase 4-hydroxy-2-quinolone, securing a reliable supply chain is essential. When looking for a 4-hydroxy-2-quinolone supplier, prioritize those who can guarantee high purity (typically 97% minimum) and provide comprehensive documentation. Manufacturers in chemical production hubs like China are often well-equipped to supply this intermediate, offering competitive 4-hydroxy-2-quinolone price points, especially for bulk orders. Partnering with a reputable 4-hydroxy-2-quinolone manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures quality and consistent availability, facilitating uninterrupted research and production schedules.

In conclusion, 4-Hydroxy-2-quinolone (CAS 86-95-3) is a valuable chemical intermediate, primarily leveraged by the pharmaceutical industry for its essential role in API synthesis. Its well-defined chemical properties and versatile reactivity make it a cornerstone compound for many advanced organic synthesis projects.