In the dynamic field of chemical research and pharmaceutical development, understanding the properties and applications of specific compounds is crucial. 4-Aminobenzamidine Dihydrochloride (CAS No. 2498-50-2) is a compound that garners significant attention due to its unique chemical characteristics and its wide-ranging uses, particularly as a protease inhibitor and a pharmaceutical intermediate.

Chemical Profile and Properties

4-Aminobenzamidine Dihydrochloride is an organic compound with the molecular formula C7H9N3·2HCl and a molecular weight of approximately 208.09 g/mol. It typically appears as an off-white to yellow powder. Key chemical properties that make it valuable include its ability to act as a competitive inhibitor of serine proteases, such as trypsin. This inhibitory action stems from its structural similarity to the natural substrates of these enzymes, allowing it to bind to the enzyme's active site. Its solubility in various solvents, including DMSO and water, also facilitates its use in laboratory settings. Researchers looking for reliable chemical information often search for the specific CAS number 2498-50-2 to ensure they are referencing the correct substance.

Applications in Research and Synthesis

The primary research application of 4-Aminobenzamidine Dihydrochloride is in the study of enzymes, particularly proteases. Its inhibitory capabilities are instrumental in understanding enzyme kinetics, mechanism of action, and the role of proteases in various biological processes. Furthermore, this compound is a vital intermediate in the synthesis of pharmaceutical products. It is a key precursor for drugs like dabigatran etexilate, a direct thrombin inhibitor used as an anticoagulant. This dual functionality makes it a highly sought-after chemical for both academic research institutions and commercial pharmaceutical companies. Laboratories often need to buy 4-aminobenzamidine dihydrochloride for ongoing research projects or small-scale synthesis.

Sourcing the Compound: Availability and Considerations

For researchers and manufacturers, sourcing high-quality 4-Aminobenzamidine Dihydrochloride is essential. Reputable chemical suppliers and manufacturers, often found internationally including those based in China, provide this compound. When you purchase 4-aminobenzamidine dihydrochloride, it's important to consider factors such as purity, lot-to-lot consistency, and the availability of supporting documentation like Certificates of Analysis. The price can vary based on the supplier, purity, and quantity ordered. Accessing this compound reliably ensures uninterrupted progress in scientific discovery and drug development.

In essence, 4-Aminobenzamidine Dihydrochloride is a compound of significant scientific and industrial importance. Its chemical properties lend themselves to critical roles in enzyme inhibition research and the synthesis of vital pharmaceuticals. Ensuring a consistent and high-quality supply through trusted vendors is a key strategy for any organization leveraging this versatile chemical.