In the realm of organic synthesis, understanding the precise properties of chemical intermediates is fundamental for successful reaction design and execution. (S)-(+)-3-Chloro-1,2-propanediol (CAS 60827-45-4) is a chiral molecule whose physical and chemical characteristics are key to its utility. For chemists and formulators looking to buy or use this compound, a clear grasp of these properties ensures optimal application and predictable outcomes.

Core Chemical and Physical Properties:

As a supplier of fine chemicals, NINGBO INNO PHARMCHEM CO.,LTD. ensures that our (S)-(+)-3-Chloro-1,2-propanediol meets rigorous quality standards. Here are some of its critical properties:

  • Molecular Formula: C3H7ClO2
  • Molecular Weight: 110.54 g/mol
  • Appearance: Typically a clear, colorless to pale yellow liquid.
  • Boiling Point: Approximately 213 °C (at standard pressure, though often distilled at reduced pressure, e.g., 80°C at 0.5 mmHg). This high boiling point indicates its stability under moderate heating.
  • Density: Around 1.322 g/mL at 25 °C. Its density is higher than water, which is a common characteristic of halogenated organic compounds.
  • Refractive Index: Approximately n20/D 1.480. This optical property is useful for identification and purity assessment.
  • Solubility: It is completely miscible with water, indicating the presence of polar hydroxyl groups that facilitate hydrogen bonding. It is also soluble in many organic solvents, enhancing its versatility in various reaction media.
  • Chirality: It possesses a chiral center, specifically at the C2 position, and is supplied as the (S)-enantiomer. This is its most critical feature for asymmetric synthesis.

Implications for Synthesis and Procurement

These properties dictate how (S)-(+)-3-Chloro-1,2-propanediol behaves in chemical reactions and storage. Its solubility profile allows it to be used in both aqueous and organic reaction systems. The presence of the chlorine atom and two hydroxyl groups provides multiple sites for functionalization, making it a flexible building block for chemists. When purchasing this compound, it is vital to verify these specifications with your supplier to ensure they align with your specific synthesis requirements.

For researchers and industrial chemists looking to buy reliable (S)-(+)-3-Chloro-1,2-propanediol, NINGBO INNO PHARMCHEM CO.,LTD. offers materials with verified properties. Our commitment as a manufacturer ensures that you receive accurate technical data and consistent product quality for all your synthetic chemistry needs.