Exploring the Chemical Properties and Safety of (S)-3-Hydroxypyrrolidine Hydrochloride
Understanding the chemical properties and safety profile of any chemical compound is paramount for its effective and responsible use in research, development, and manufacturing. (S)-3-Hydroxypyrrolidine hydrochloride (CAS 122536-94-1) is no exception. This chiral intermediate, vital for pharmaceutical synthesis, possesses specific characteristics that dictate its handling, storage, and application.
Chemically, (S)-3-Hydroxypyrrolidine hydrochloride is known for its white crystalline powder appearance. Its molecular formula is C4H10ClNO, with a molecular weight of approximately 123.58 g/mol. The compound typically exhibits a melting point in the range of 104-107°C. Its solubility is generally described as sparingly soluble in DMSO and slightly soluble in methanol, indicating its compatibility with certain organic reaction solvents.
Stability and handling are crucial considerations. The compound is noted to be hygroscopic, meaning it absorbs moisture from the air, and can be sensitive to air. Therefore, proper storage conditions are essential to maintain its integrity. Keeping the container tightly closed in a dry and well-ventilated place is recommended. Incompatible materials, such as strong oxidizing agents, should be avoided.
From a safety perspective, (S)-3-Hydroxypyrrolidine hydrochloride is classified with certain hazard statements, including H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Consequently, appropriate personal protective equipment (PPE) is necessary when handling this chemical. This includes safety goggles or a face shield, chemical-resistant gloves, and adequate ventilation or respiratory protection. Standard laboratory safety practices, such as avoiding inhalation of dust and preventing contact with skin and eyes, must be strictly followed.
Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. provide detailed Safety Data Sheets (SDS) for their products, which offer comprehensive information on hazards, handling, storage, and emergency procedures. Users are strongly advised to consult the SDS before working with (S)-3-Hydroxypyrrolidine hydrochloride to ensure safe laboratory and industrial operations.
By adhering to these guidelines, researchers and manufacturers can effectively and safely utilize (S)-3-Hydroxypyrrolidine hydrochloride in their synthetic endeavors, ensuring both product quality and workplace safety.
Chemically, (S)-3-Hydroxypyrrolidine hydrochloride is known for its white crystalline powder appearance. Its molecular formula is C4H10ClNO, with a molecular weight of approximately 123.58 g/mol. The compound typically exhibits a melting point in the range of 104-107°C. Its solubility is generally described as sparingly soluble in DMSO and slightly soluble in methanol, indicating its compatibility with certain organic reaction solvents.
Stability and handling are crucial considerations. The compound is noted to be hygroscopic, meaning it absorbs moisture from the air, and can be sensitive to air. Therefore, proper storage conditions are essential to maintain its integrity. Keeping the container tightly closed in a dry and well-ventilated place is recommended. Incompatible materials, such as strong oxidizing agents, should be avoided.
From a safety perspective, (S)-3-Hydroxypyrrolidine hydrochloride is classified with certain hazard statements, including H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Consequently, appropriate personal protective equipment (PPE) is necessary when handling this chemical. This includes safety goggles or a face shield, chemical-resistant gloves, and adequate ventilation or respiratory protection. Standard laboratory safety practices, such as avoiding inhalation of dust and preventing contact with skin and eyes, must be strictly followed.
Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. provide detailed Safety Data Sheets (SDS) for their products, which offer comprehensive information on hazards, handling, storage, and emergency procedures. Users are strongly advised to consult the SDS before working with (S)-3-Hydroxypyrrolidine hydrochloride to ensure safe laboratory and industrial operations.
By adhering to these guidelines, researchers and manufacturers can effectively and safely utilize (S)-3-Hydroxypyrrolidine hydrochloride in their synthetic endeavors, ensuring both product quality and workplace safety.
Perspectives & Insights
Agile Reader One
“Understanding the chemical properties and safety profile of any chemical compound is paramount for its effective and responsible use in research, development, and manufacturing.”
Logic Vision Labs
“This chiral intermediate, vital for pharmaceutical synthesis, possesses specific characteristics that dictate its handling, storage, and application.”
Molecule Origin 88
“Chemically, (S)-3-Hydroxypyrrolidine hydrochloride is known for its white crystalline powder appearance.”