1-Bromoadamantane (CAS 768-90-1) is a fascinating molecule characterized by its rigid adamantane cage structure and the presence of a bromine atom, which makes it a reactive and valuable intermediate in various chemical synthesis processes. Understanding its chemical properties and synthesis routes is essential for chemists and researchers. NINGBO INNO PHARMCHEM CO.,LTD., as a producer and supplier, offers insights into this compound.

Chemically, 1-Bromoadamantane (C10H15Br) is known for its relatively high melting point, typically in the range of 116-118 °C. Its solubility profile indicates it is sparingly soluble in chloroform and slightly soluble in ethyl acetate and methanol, while being largely insoluble in water. This lipophilic nature, combined with the tertiary bromide, makes it susceptible to SN1 reactions. The adamantane framework itself is thermally stable and chemically inert under many conditions, providing a robust scaffold for functionalization.

The synthesis of 1-Bromoadamantane often starts from adamantane itself. A common method involves the bromination of adamantane using reagents like elemental bromine or N-bromosuccinimide (NBS) under specific reaction conditions, often involving Lewis acid catalysts or radical initiators. Another approach might involve the conversion of 1-adamantanol to 1-Bromoadamantane using brominating agents such as phosphorus tribromide (PBr3) or hydrobromic acid (HBr). The exact choice of synthesis route depends on factors like desired purity, yield, and cost-effectiveness.

The purity of synthesized 1-Bromoadamantane is crucial for its downstream applications, especially in the pharmaceutical sector. NINGBO INNO PHARMCHEM CO.,LTD. ensures a high assay of ≥98.0% through controlled manufacturing processes and purification techniques, such as recrystallization. This commitment to quality means that clients can reliably buy 1-Bromoadamantane for their demanding synthesis needs, whether it's for amantadine production or other complex organic transformations.

For manufacturers and researchers seeking to source this chemical, partnering with a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. is paramount. We provide consistent quality, competitive pricing, and a stable supply chain, making us an ideal choice for your procurement needs. We encourage inquiries to learn more about our product specifications and to discuss how we can support your projects requiring 1-Bromoadamantane.

In summary, the chemical properties and accessible synthesis routes of 1-Bromoadamantane make it a cornerstone intermediate in various chemical disciplines, underscoring its importance in modern synthetic chemistry.