Understanding the fundamental chemical properties and synthesis pathways of key organic intermediates is crucial for efficient and innovative chemical manufacturing. 1-Chloro-3-fluorobenzene (CAS: 625-98-9), a halogenated aromatic hydrocarbon, is a prime example of such an intermediate, widely used across diverse industries. Its unique structural configuration and reactivity patterns make it a valuable compound for various synthetic applications.

Chemical Identity and Properties of 1-Chloro-3-fluorobenzene

1-Chloro-3-fluorobenzene is a derivative of benzene featuring both a chlorine and a fluorine atom substituted at the meta (1,3) positions of the benzene ring. Its molecular formula is C6H4ClF, with a molecular weight of approximately 130.55 g/mol. Key physical and chemical properties that define its utility include:

  • Appearance: Typically a transparent, colorless to pale yellow liquid.
  • Density: Around 1.219 g/mL at 25°C.
  • Boiling Point: Approximately 126-128°C.
  • Flash Point: Around 68°F, classifying it as a flammable liquid and requiring careful handling.
  • Purity: Commonly available at purities of ≥99.0%.
  • Reactivity: The electron-withdrawing nature of chlorine and fluorine atoms influences the aromatic ring's reactivity, particularly in electrophilic and nucleophilic aromatic substitution reactions. This dual halogen substitution offers specific regioselectivity advantages in complex syntheses.

These properties dictate its handling, storage, and application in laboratory and industrial settings. As a product of organic synthesis, understanding its precise specifications is key for anyone looking to buy 1-Chloro-3-fluorobenzene.

Synthesis Routes and Manufacturing Considerations

While the specifics of large-scale industrial synthesis routes are often proprietary, literature suggests several pathways to produce 1-Chloro-3-fluorobenzene. These often involve selective halogenation or transformations of precursor aromatic compounds. The efficiency, yield, and environmental impact of these synthesis methods are critical considerations for manufacturers.

For industries relying on this intermediate, such as pharmaceutical and agrochemical sectors, sourcing from a reputable 1-Chloro-3-fluorobenzene manufacturer China is a strategic decision. These manufacturers often possess the expertise and infrastructure to produce the compound consistently at high purity levels (≥99.0%).

When evaluating suppliers, it is important to inquire about their manufacturing processes, quality control measures, and the availability of supporting documentation like SDS and CoA. Understanding the 1-Chloro-3-fluorobenzene price in relation to these quality assurances provides a clear picture of value.

In summary, the detailed chemical properties and synthesis considerations of 1-Chloro-3-fluorobenzene underscore its importance as a versatile organic intermediate. By engaging with knowledgeable suppliers who prioritize quality and offer transparent production information, industries can effectively harness its potential in their synthetic endeavors.