For scientists and engineers working with fine chemicals, a deep understanding of a compound's properties and synthesis is crucial for successful application and procurement. 2,3-Dihydrobenzofuran-5-carboxylic acid (CAS 76429-73-7) is a prime example of such a compound, valued for its specific chemical characteristics and its role as a versatile intermediate. Whether you're looking to buy it for research or need to understand its production, this information is key.

Chemical Identity and Key Specifications

2,3-Dihydrobenzofuran-5-carboxylic acid, with the molecular formula C₉H₈O₃ and a molecular weight of 164.16 g/mol, is an organic compound featuring a dihydrobenzofuran core with a carboxylic acid group at the 5-position. The CAS number 76429-73-7 uniquely identifies this substance. Typically supplied as a powder, its purity is a critical specification, often stated as 97% minimum, ensuring its suitability for sensitive synthetic processes. Understanding these basic identifiers helps in accurately locating and procuring the material from a reliable supplier.

Key Chemical Properties and Reactivity

The reactivity of 2,3-Dihydrobenzofuran-5-carboxylic acid is largely dictated by its functional groups. The carboxylic acid moiety allows for typical reactions such as esterification with alcohols and reduction to the corresponding alcohol. The dihydrobenzofuran ring system, while less aromatic than benzofuran itself, provides a stable scaffold that can participate in various electrophilic substitution reactions under appropriate conditions. Its physical properties, such as a melting point typically around 185℃ and a boiling point of approximately 336.55℃, are important for handling and process design. When sourcing this material, always confirm these details with the manufacturer.

Common Synthesis Routes

The synthesis of 2,3-Dihydrobenzofuran-5-carboxylic acid can be achieved through several methods, often involving cyclization reactions or modifications of existing benzofuran structures. One common approach involves the hydrolysis of ester precursors. Another involves palladium-catalyzed reactions that facilitate ring closure and functionalization. Researchers are also exploring greener synthetic routes, such as visible-light-mediated catalysis, to improve efficiency and reduce environmental impact. Knowing these synthesis pathways can help in appreciating the complexity and value when you purchase this intermediate.

For those in the market to acquire this essential compound, understanding its chemical properties and how it's synthesized provides a solid foundation for making informed purchasing decisions. Engaging with a reputable manufacturer in China for 2,3-Dihydrobenzofuran-5-carboxylic acid ensures access to a well-characterized product vital for groundbreaking research and industrial applications.