The Chemical Properties and Synthesis of 2-Chlorobenzoyl Chloride
Understanding the fundamental chemical properties and synthesis pathways of key intermediates is essential for their effective application in various industries. 2-Chlorobenzoyl chloride (CAS 609-65-4) is a prime example, valued for its specific chemical characteristics and its role in creating more complex compounds. As a chemical manufacturer, we provide this insight to assist researchers and production managers in their operations.
The molecular formula of 2-Chlorobenzoyl chloride is C7H4Cl2O, and it possesses a molecular weight of approximately 175.01 g/mol. Its structure features a benzene ring substituted with a chlorine atom at the ortho position and an acyl chloride group. This arrangement dictates its reactivity. As an acyl chloride, it is highly reactive towards nucleophiles, readily undergoing reactions like esterification and amidation. Its boiling point is around 238°C, and it is sensitive to moisture, typically decomposing in the presence of water. These properties necessitate careful handling and storage in dry conditions.
The synthesis of 2-Chlorobenzoyl chloride commonly involves the reaction of 2-chlorobenzoic acid with a chlorinating agent, such as thionyl chloride (SOCl2) or phosphorus pentachloride (PCl5). A typical laboratory or industrial synthesis might involve reacting 2-chlorobenzoic acid with thionyl chloride under reflux conditions, often with a catalytic amount of dimethylformamide (DMF). The byproduct gases, sulfur dioxide and hydrogen chloride, are then removed, and the desired 2-Chlorobenzoyl chloride is purified, often by distillation. Achieving a high purity of 99% or more is a key objective in its production, ensuring its suitability for sensitive applications in pharmaceutical and agrochemical synthesis.
Our manufacturing facilities are equipped to perform these syntheses efficiently and safely, adhering to strict quality control measures. The ability to consistently produce high-purity 2-Chlorobenzoyl chloride is a testament to our expertise in chemical synthesis. For those seeking to purchase this intermediate or requiring specific technical data such as Safety Data Sheets (SDS) or Certificates of Analysis (CoA), contacting our sales department is the recommended course of action. We are committed to providing the chemical community with reliable access to essential building blocks.
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