Understanding the detailed chemical profile of 2-Cyano-5-Fluorobenzyl Bromide (CAS: 421552-12-7) is essential for R&D scientists and formulators. This compound, with the molecular formula C8H5BrFN and a molecular weight of 214.03400, is a white to yellow solid. Its physical properties, such as a density of 1.591 g/cm³, a boiling point of approximately 264.468°C, and a flash point of 113.746°C, provide critical insights for handling and process design. These characteristics make it a stable yet reactive intermediate, ideal for various synthetic applications, particularly in the pharmaceutical sector.

The synthesis of 2-Cyano-5-Fluorobenzyl Bromide typically involves reactions starting from precursor molecules containing the fluorinated benzonitrile structure. For instance, one common route begins with 4-fluoro-2-methylbenzonitrile, which is then subjected to bromination, often using N-bromosuccinimide (NBS) under specific reaction conditions. The process requires careful control of temperature, reaction time, and reagents to achieve high yields and purity. For those looking to buy 2-Cyano-5-Fluorobenzyl Bromide, inquiring about the synthesis route and quality control measures from a reputable 2-Cyano-5-Fluorobenzyl Bromide manufacturer is advisable.

As a crucial Trelagliptin intermediate, the purity of 2-Cyano-5-Fluorobenzyl Bromide is paramount. Suppliers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., ensure that their product consistently meets ≥98.0% purity standards via HPLC, making it suitable for sensitive pharmaceutical manufacturing processes. When seeking a reliable supplier of CAS 421552-12-7, it’s important to consider their technical expertise, production capacity, and ability to provide necessary documentation like Certificates of Analysis (CoA) and Safety Data Sheets (SDS). This ensures compliance and smooth integration into your R&D or manufacturing workflow.

The availability of this compound from experienced manufacturers allows pharmaceutical companies to efficiently produce life-saving medications. If you are in the market to purchase this essential chemical, engaging with a trusted pharmaceutical intermediate manufacturer will ensure you receive a product that meets your exacting specifications. For quotes and further information on our 2-Cyano-5-Fluorobenzyl Bromide, please feel free to contact us.