3-Bromochlorobenzene (CAS 108-37-2) is a halogenated aromatic hydrocarbon that holds significant importance in organic chemistry, serving as a versatile intermediate. Understanding its chemical properties and common synthesis pathways is crucial for researchers and manufacturers aiming to utilize it effectively in various applications, from pharmaceuticals to specialty chemicals.

Chemically, 3-Bromochlorobenzene is characterized by a benzene ring substituted with a bromine atom and a chlorine atom at the meta positions. Its molecular formula is C6H4BrCl, with a molecular weight of approximately 191.45 g/mol. As a physical property, it appears as a clear, colorless to light yellow liquid. Key physical data includes a density of around 1.63 g/cm³, a boiling point of approximately 196°C, and a refractive index of 1.576. These properties are vital for process control and optimization in industrial synthesis. The compound's stability, combined with the differential reactivity of the C-Br and C-Cl bonds, makes it a valuable starting material for selective functionalization.

The synthesis of 3-Bromochlorobenzene can be achieved through several routes. A common method involves the Sandmeyer reaction. Starting with 3-chloroaniline, diazotization with sodium nitrite and acid (like HBr) forms the diazonium salt. This intermediate is then treated with cuprous bromide (CuBr) and hydrobromic acid (HBr) at elevated temperatures to replace the diazonium group with a bromine atom, yielding 3-Bromochlorobenzene. Other synthetic strategies might involve electrophilic substitution reactions on appropriately substituted benzene precursors.

For procurement professionals and laboratory chemists, sourcing high-quality 3-Bromochlorobenzene is essential. When you look to buy this compound, ensuring a purity of 99.0% or higher is standard practice, especially for sensitive applications. Manufacturers often provide detailed product specifications and COAs. If you are in need of this intermediate, consider contacting established chemical suppliers and manufacturers in China who can provide consistent quality and competitive pricing. We specialize in providing high-purity 3-Bromochlorobenzene to meet the diverse needs of the chemical industry.

In summary, 3-Bromochlorobenzene is a compound with well-defined chemical and physical properties that underpin its utility in organic synthesis. Its synthesis via methods like the Sandmeyer reaction, and its application as a versatile intermediate, make it a staple in many chemical laboratories and industrial production facilities. Understanding these aspects can help you make informed decisions when sourcing this important chemical.