The Chemical Properties and Synthesis of 4-Acetyl-2-methylbenzoic Acid
Understanding the intrinsic chemical properties and reliable synthesis routes of key intermediates is fundamental for progress in chemical manufacturing and research. 4-Acetyl-2-methylbenzoic Acid, bearing the CAS number 55860-35-0, is a compound of significant interest due to its versatile role as a building block in organic synthesis and as a pharmaceutical intermediate.
The compound's chemical profile reveals it as an aromatic carboxylic acid with a molecular weight of 178.18 g/mol and the formula C10H10O3. Key physical properties often cited include its appearance as a white to light yellow crystalline powder or solid, with a melting point typically in the range of 168-172 °C. Its solubility characteristics are also important; it is generally soluble in common organic solvents like DMSO and methanol, but sparingly soluble in water. These properties guide its handling, storage, and application in various reaction conditions.
The synthesis of 4-Acetyl-2-methylbenzoic Acid can be achieved through several established methods. Common routes involve starting materials such as 4-acetyl-2-methylbenzonitrile or 3-methyl-4-cyanoacetophenone, which are then subjected to hydrolysis or other functional group transformations. The optimization of these synthesis methods aims to achieve high yields and purity, which are critical for its subsequent use as a pharmaceutical intermediate or in other fine chemical applications.
Beyond its synthesis, the reactivity of 4-Acetyl-2-methylbenzoic Acid, particularly its carboxylic acid and acetyl functionalities, allows for a range of chemical reactions, including esterification and nucleophilic attacks. These reactions are the basis for its utility in constructing more complex molecular structures. Companies like NINGBO INNO PHARMCHEM CO.,LTD. focus on ensuring the consistent quality and availability of such intermediates, supporting the intricate needs of the chemical and pharmaceutical industries. Their expertise in chemical synthesis and supply chain management is vital for researchers and manufacturers relying on precise chemical building blocks.
Perspectives & Insights
Chem Catalyst Pro
“The optimization of these synthesis methods aims to achieve high yields and purity, which are critical for its subsequent use as a pharmaceutical intermediate or in other fine chemical applications.”
Agile Thinker 7
“Beyond its synthesis, the reactivity of 4-Acetyl-2-methylbenzoic Acid, particularly its carboxylic acid and acetyl functionalities, allows for a range of chemical reactions, including esterification and nucleophilic attacks.”
Logic Spark 24
“These reactions are the basis for its utility in constructing more complex molecular structures.”